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001438064 001__ 1438064
001438064 003__ OCoLC
001438064 005__ 20230309004246.0
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001438064 019__ $$a1259592580$$a1266811075
001438064 020__ $$a9783030756994$$q(electronic bk.)
001438064 020__ $$a3030756998$$q(electronic bk.)
001438064 020__ $$z303075698X
001438064 020__ $$z9783030756987
001438064 0247_ $$a10.1007/978-3-030-75699-4$$2doi
001438064 035__ $$aSP(OCoLC)1260190515
001438064 040__ $$aYDX$$beng$$epn$$cYDX$$dGW5XE$$dEBLCP$$dOCLCO$$dOCLCF$$dDCT$$dUKAHL$$dN$T$$dOCLCO$$dCOM$$dOCLCQ
001438064 049__ $$aISEA
001438064 050_4 $$aRC268.5
001438064 08204 $$a616.99/4071$$223
001438064 1001_ $$aCarlberg, Carsten,$$eauthor.
001438064 24510 $$aCancer biology :$$bhow science works /$$cCarsten Carlberg, Eunike Velleuer.
001438064 260__ $$aCham :$$bSpringer,$$c2021.
001438064 300__ $$a1 online resource
001438064 336__ $$atext$$btxt$$2rdacontent
001438064 337__ $$acomputer$$bc$$2rdamedia
001438064 338__ $$aonline resource$$bcr$$2rdacarrier
001438064 347__ $$atext file
001438064 347__ $$bPDF
001438064 504__ $$aIncludes bibliographical references.
001438064 5050_ $$a1. Introduction to cancer -- 2. Oncogenes, signal transduction and the hallmarks of cancer -- 3. Tumor suppressor genes and cell fate control -- 4. Multi-step tumorigenesis and genome instability -- 5. Cancer genomics -- 6. Cancer epigenomics -- 7. Aging and cancer -- 8. Tumor microenvironment -- 9. Metastasis and cachexia -- 10. Cancer immunity -- 11. Architecture of cancer therapies.
001438064 506__ $$aAccess limited to authorized users.
001438064 520__ $$aCancer is a collection of diseases that can affect basically every organ of our body, all of which have in common uncontrolled cellular growth. The cells forming our body have the potential to grow in the context of wound healing or for the constant replacement of cells in our blood, skin or intestine. Behind every newly diagnosed malignant tumor in adulthood there is an individual history of probably 20 or more years of tumorigenesis. Therefore, malignant tumor formation often takes time making cancer in most cases to an aging-related disease that we seem not to be able to evade. However, tumorigenesis is dependent on multiple environmental influences, many of which we have under control by lifestyle decisions, such as retaining from smoking, selecting healthy food and being physically active. Thus, cancer preventive interventions are the most effective way to fight against cancer. This textbook wants not only to describe basic mechanisms leading to cancer but also to provide the readers with a more holistic view including cancer surveaillance mechanisms of the immune system. We will place these insights in the context of the personal consequences of everyone's lifestyle decisions.
001438064 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed July 16, 2021).
001438064 650_0 $$aCarcinogenesis.
001438064 650_0 $$aCancer$$xEtiology.
001438064 650_6 $$aCancérogenèse.
001438064 650_6 $$aCancer$$xÉtiologie.
001438064 655_0 $$aElectronic books.
001438064 7001_ $$aVelleuer, Eunike,$$eauthor$$0(orcid)0000-0003-4328-9556$$1https://orcid.org/0000-0003-4328-9556
001438064 77608 $$iPrint version:$$z303075698X$$z9783030756987$$w(OCoLC)1245659035
001438064 852__ $$bebk
001438064 85640 $$3Springer Nature$$uhttps://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-3-030-75699-4$$zOnline Access$$91397441.1
001438064 909CO $$ooai:library.usi.edu:1438064$$pGLOBAL_SET
001438064 980__ $$aBIB
001438064 980__ $$aEBOOK
001438064 982__ $$aEbook
001438064 983__ $$aOnline
001438064 994__ $$a92$$bISE