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001438199 019__ $$a1260192185$$a1266810318
001438199 020__ $$a9783030732271$$q(electronic bk.)
001438199 020__ $$a3030732274$$q(electronic bk.)
001438199 020__ $$z9783030732264
001438199 0247_ $$a10.1007/978-3-030-73227-1$$2doi
001438199 035__ $$aSP(OCoLC)1260344215
001438199 040__ $$aEBLCP$$beng$$epn$$cEBLCP$$dYDX$$dGW5XE$$dOCLCO$$dOCLCF$$dN$T$$dDCT$$dUKAHL$$dOCLCQ$$dOCLCO$$dOCLCQ
001438199 049__ $$aISEA
001438199 050_4 $$aRC270
001438199 08204 $$a616.99/4075$$223
001438199 24500 $$aPractical oncologic molecular pathology :$$bfrequently asked questions /$$cYi Ding, Linsheng Zhang, editors.
001438199 260__ $$aCham :$$bSpringer,$$c2021.
001438199 300__ $$a1 online resource (446 pages)
001438199 336__ $$atext$$btxt$$2rdacontent
001438199 337__ $$acomputer$$bc$$2rdamedia
001438199 338__ $$aonline resource$$bcr$$2rdacarrier
001438199 347__ $$atext file
001438199 347__ $$bPDF
001438199 4901_ $$aPractical Anatomic Pathology
001438199 500__ $$aGenetic Testing.
001438199 500__ $$aIncludes index.
001438199 5050_ $$aIntro -- Preface -- Contents -- Contributors -- Part I: Molecular Methods and Data Analysis in Clinical Molecular Diagnostic Laboratories -- 1: The Molecular Pathobiology of Malignant Process and Molecular Diagnostic Testing for Cancer -- List of Frequently Asked Questions -- Frequently Asked Questions -- Case Presentations -- Case 1 -- Learning Objectives -- Case History -- Initial Work-up -- Histologic Findings -- Molecular Genetic Study -- Final Diagnosis -- Discussion -- Case 2 -- Learning Objectives -- Case History -- Molecular Genetic Studies -- Final Diagnosis -- Clinical Follow-Up
001438199 5058_ $$aDiscussion -- Case 3 -- Learning Objectives -- Case History -- Laboratory Findings -- Molecular Genetic Studies -- Final Diagnosis -- Discussion -- Case 4 -- Learning Objective -- Case History -- Molecular Genetic Studies -- Final Diagnosis -- Discussion -- Case 5 -- Learning Objectives -- Case History -- Molecular Genetic Studies -- Final Diagnosis -- Discussion -- References -- 2: Molecular Diagnostic Methods -- List of Frequently Asked Questions -- Frequently Asked Questions -- Case Examples -- Case #1 -- Learning Objectives -- Case History -- Final Diagnosis -- Discussion -- Case #2
001438199 5058_ $$aLearning Objectives -- Case History -- Laboratory Work-up -- Histologic Findings -- Molecular Genetic Studies -- Final Diagnosis -- Discussion -- NGS Sequencing Results -- Case #3 -- Learning Objectives -- Case History -- Final Diagnosis -- Discussion -- Case #4 -- Learning Objectives -- Case History -- Final Diagnosis -- Discussion -- References -- 3: Bioinformatics Analysis in Molecular Pathology -- List of Frequently Asked Questions -- Frequently Asked Questions -- Cases -- Case 1: HGVS Nomenclature and Rules -- Discussion for Case 1 -- Case 2: Read Depth and Molecular Bar Coding
001438199 5058_ $$aDiscussion for Case 2 -- Case 3: FASTQ Format and Mate-Pairs -- Discussion for Case 3 -- Case 4: Variant Filtering -- Discussion for Case 4 -- Case 5: Protected Health Information and Cloud Services -- Discussion for Case 5 -- References -- 4: Quality Assurance and Quality Control in Molecular Diagnostic Laboratories -- List of Frequently Asked Questions -- Frequently Asked Questions -- Case Presentations -- Case 1 -- Learning Objective -- Case History -- Case 2 -- Learning Objective -- Case History -- Case 3 -- Learning Objective -- Case History -- References
001438199 5058_ $$aPart II: Molecular Pathology of Solid and Soft Tissue Tumors -- 5: Breast and Gynecologic Tumors -- List of Frequently Asked Questions -- Frequently Asked Questions -- Case Presentations -- Case 1 -- Case History -- Histologic Finding -- Differential Diagnosis -- Ancillary Studies -- Final Diagnosis -- Discussion -- Case 2 -- History -- HER2 Testing -- Final HER2 Interpretation -- Discussion -- Case 3 -- History -- Gross Findings -- Histologic Findings -- Differential Diagnosis -- Ancillary Studies -- Final Diagnosis -- Discussion -- Case 4 -- History -- Histologic Findings -- MMR Studies
001438199 506__ $$aAccess limited to authorized users.
001438199 520__ $$aThis book is a review and high-yield reference on the clinical molecular diagnostics of malignant neoplasms. It aims to address the practical questions frequently encountered in the molecular oncology practice, as well as key points and pitfalls in the clinical interpretation of molecular tests in guiding precision cancer management. The text uses a Q & A format and case presentations, with emphasis on understanding the molecular test methods, diagnosis, classification, risk assessment and clinical correlation. Starting with an update on the molecular biology of cancer, the book focuses on the topics related to molecular diagnostics and genetics-based precision oncology. Separate chapters are dedicated to discussion of the bioinformatics for the analysis of genetic/genomic data generated from molecular assays, and quality control (QC)/quality assurance (QA) programs in the clinical laboratories; both are critical in producing high quality results for clinical care of cancer patients. These are followed by organ system-based reviews and discussions on the molecular genetic abnormalities and related tests covering diverse types of common to rare malignant neoplasms. This book also provides up-to-date knowledge related to malignant neoplasms, discusses the established as well as evolving requirements for pathologic diagnosis of these malignancies. It also discusses the cost effective utilization of molecular tests in clinical oncology. Written by experts in the field, Practical Oncologic Molecular Pathology serves as a valuable reference for practicing pathologists, fellows, residents and other health care professionals.
001438199 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed July 27, 2021).
001438199 650_0 $$aCancer$$xMolecular diagnosis.
001438199 650_6 $$aCancer$$xDiagnostic moléculaire.
001438199 655_0 $$aElectronic books.
001438199 7001_ $$aDing, Yi.
001438199 7001_ $$aZhang, Linsheng.
001438199 77608 $$iPrint version:$$aDing, Yi.$$tPractical Oncologic Molecular Pathology.$$dCham : Springer International Publishing AG, ©2021$$z9783030732264
001438199 830_0 $$aPractical anatomic pathology.
001438199 852__ $$bebk
001438199 85640 $$3Springer Nature$$uhttps://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-3-030-73227-1$$zOnline Access$$91397441.1
001438199 909CO $$ooai:library.usi.edu:1438199$$pGLOBAL_SET
001438199 980__ $$aBIB
001438199 980__ $$aEBOOK
001438199 982__ $$aEbook
001438199 983__ $$aOnline
001438199 994__ $$a92$$bISE