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5: Age-Specific Differences in the Severity of COVID-19 Between Children and Adults: Reality and Reasons
1 Introduction
2 Age-Related Effects of Different Infections
3 Age Effects of COVID-19 Disease
4 Clinical Features in Children
5 The Different Etiology and Severity of COVID-19 Based on Age
6 Underlying Conditions and Severity of COVID-19 in Children
7 Outdoor Activities and the Potential to Contract the Virus
8 Immune System and Age-Related Differences
9 Innate Immune Cells and Age-Related Differences
10 IFN and SARS-CoV in Children

Intro
Preface
Contents
Part I: Background
1: Genetic Aspects and Immune Responses in Covid-19: Important Organ Involvement
1 Introduction
2 Epidemiology
3 Main Coronavirus Groups
4 Genome, Genotype, and Protein Structure
5 Mechanism of Infection
6 COVID-19 Pathogenesis
7 Respiratory Manifestations
8 Extra-pulmonary Presentations
8.1 Gastrointestinal Manifestations
8.2 Cardiovascular Complications
8.3 Haematological Disorders
9 Immune Responses
10 Therapy
10.1 Drugs that Slow Viral Replication or Kill SARS-Cov-2

10.2 Vaccination
11 Conclusion
References
Part II: Epidemiology
2: Prevalence of COVID-19 and the Continued Citizen-Based Control in Japan
1 Introduction
2 Cruise Ship Outbreak and the Environmental Assessment
2.1 COVID-19 Outbreak on the Diamond Princess Cruise Ship
2.2 Age-Related CFR Estimated from the Cruise Ship Outbreak
2.3 Environmental Assessment of SARS-CoV-2 on the Cruise Ship
3 Government-Recommended and Voluntary Measures to Protect Against COVID-19 Infection in Japan
4 Detection of the Coronavirus in Laboratories in Japan
5 Conclusions

3.1 Theme I: Emotional-Sensational-Paradox
Satisfaction-Dissatisfaction
Positive Experiences-Negative Experiences
Relaxation-Stress
Support-Rejection
3.2 Theme II: Spiritual Growth
Accepting and Submitting to Divine Providence
Rethinking Material Possessions
Seeking Stronger Divine Connection
Tendency to Spirituality
3.3 Theme III: Experienced Mental-Psychological Effects
Unpleasant Thoughts
Perceived Mental Stress
Positive Thoughts
4 Discussion
5 Conclusions
References
Part III: Risk Factors and Outcomes

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