001438428 000__ 05205cam\a2200553\a\4500 001438428 001__ 1438428 001438428 003__ OCoLC 001438428 005__ 20230309004304.0 001438428 006__ m\\\\\o\\d\\\\\\\\ 001438428 007__ cr\un\nnnunnun 001438428 008__ 210725s2021\\\\sz\\\\\\o\\\\\001\0\eng\d 001438428 019__ $$a1262374237 001438428 020__ $$a9783030762018$$q(electronic bk.) 001438428 020__ $$a3030762017$$q(electronic bk.) 001438428 020__ $$z3030762009 001438428 020__ $$z9783030762001 001438428 0247_ $$a10.1007/978-3-030-76201-8$$2doi 001438428 035__ $$aSP(OCoLC)1261379817 001438428 040__ $$aYDX$$beng$$epn$$cYDX$$dGW5XE$$dEBLCP$$dOCLCO$$dOCLCF$$dUKAHL$$dOCLCQ$$dOCLCO$$dSFB$$dOCLCQ 001438428 049__ $$aISEA 001438428 050_4 $$aRC346 001438428 08204 $$a616.99/4711$$223 001438428 24500 $$aChordoma of the spine :$$ba comprehensive review /$$cDaniel M. Sciubba, Joseph H. Schwab, editors. 001438428 260__ $$aCham :$$bSpringer,$$c2021. 001438428 300__ $$a1 online resource 001438428 336__ $$atext$$btxt$$2rdacontent 001438428 337__ $$acomputer$$bc$$2rdamedia 001438428 338__ $$aonline resource$$bcr$$2rdacarrier 001438428 500__ $$aIncludes index. 001438428 504__ $$aReferences-5: Histopathologic Classification of Spinal Chordoma-Introduction-Benign Notochordal Tumor-Conventional Chordoma-Dedifferentiated Chordoma-Poorly Differentiated Chordoma-Conclusion-References-6: Multidisciplinary Planning for Treatment of Chordoma-Introduction-Basis for a Multidisciplinary Approach-Diagnosis and Staging-Diagnostic Radiology and Interventional Radiology-Pathology-Neoadjuvant and Adjuvant Treatments-Radiation Oncology-Medical Oncology-Surgical Care-Perioperative Care-Establishing Surgical Goals. 001438428 5050_ $$aSection I Pathophysiology and Molecular Mechanisms of Chordoma -- Notochordal Morphogenesis and the Origin of Chordoma -- Molecular and Genetic Mechanisms of Spinal Chordoma -- Section II Epidemiology, Clinical History, and Work-Up for Chordoma.-Historical Overview, Demographics, and Clinical Presentation of Spinal Chordoma -- Clinical Work up, Diagnostic Imaging and Biopsy -- Histopathologic Classification of Spinal Chordoma -- Multi-disciplinary Planning for Treatment -- Section III Surgical Management of Chordoma -- Surgical Management of Chordoma of the Occipitocervical Junction -- Surgical Management of Chordoma of the Cervical Spine -- Surgical Management of Chordoma of the Thoracic Spine -- Surgical Management of Chordoma of the Lumbar Spine -- Surgical Management of Chordoma of the Sacrum -- Soft Tissue Reconstruction Following Surgery for Sacral Chordoma -- Vascular Reconstruction After EnBloc Resection -- Section IV Radiation and Chemotherapeutic Adjuvants for Chordoma -- Photon Therapy for Chordoma of the Spine -- Heavy Particle Therapy for Chordoma -- Systemic Therapy, Trials and Future Directions for Chordoma of the Spine -- Index. 001438428 506__ $$aAccess limited to authorized users. 001438428 520__ $$aThis book provides a comprehensive review of the epidemiology, pathogenesis, diagnosis, and management of chordomas of the mobile spine and sacrum. Historically, knowledge about how to deliver such state-of-the-art care has not been widespread, resulting in inconsistent treatment, and, all too often, suboptimal outcomes for chordoma patients. This text is an important step towards broadening that knowledge, and, in turn, improving the care provided to chordoma patients. The book is divided into 4 parts comprising 16 chapters. The first part focuses on the pathophysiology and molecular drivers of chordoma. The second focuses on the epidemiology and clinical history, as well as the histological, oncologic, and radiographic work-up of chordoma. The third part focuses primarily on the technical aspects of surgery for chordoma. It is broken down by anatomic region, with the final two chapters focusing on the soft tissue and bony reconstruction following chordoma resection. The last part focuses on the exciting field of adjuvant therapies for chordoma. This includes both radiation therapies and novel chemotherapeutic options for recurrent, metastatic, and dedifferentiated chordoma. Written by world experts from leading chordoma centers, Chordoma of the Spine serves as a valuable reference for spinal oncologists and general spine surgeons who may encounter chordoma patients in their practice. It provides the most up-to-date evidence regarding all aspects of treating patients with this disease. By focusing on this specific pathology of the spine, this resource condenses expert-level research into understandable treatment algorithms. 001438428 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed August 4, 2021). 001438428 650_0 $$aChordoma. 001438428 650_0 $$aSpine$$xCancer. 001438428 650_6 $$aChordome. 001438428 650_6 $$aColonne vertébrale$$xCancer. 001438428 655_7 $$aLlibres electrònics.$$2thub 001438428 655_0 $$aElectronic books. 001438428 7001_ $$aSciubba, Daniel M.,$$eeditor. 001438428 7001_ $$aSchwab, Joseph H.,$$eeditor. 001438428 77608 $$iPrint version:$$tChordoma of the spine.$$dCham : Springer, 2021$$z3030762009$$z9783030762001$$w(OCoLC)1246352531 001438428 852__ $$bebk 001438428 85640 $$3Springer Nature$$uhttps://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-3-030-76201-8$$zOnline Access$$91397441.1 001438428 909CO $$ooai:library.usi.edu:1438428$$pGLOBAL_SET 001438428 980__ $$aBIB 001438428 980__ $$aEBOOK 001438428 982__ $$aEbook 001438428 983__ $$aOnline 001438428 994__ $$a92$$bISE