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001439243 08204 $$a615.9/42$$223
001439243 1001_ $$aMukherjee, Ashis K.,$$eauthor.
001439243 24514 $$aThe 'big four' snakes of India :$$bvenom composition, pharmacological properties and treatment of envenomation /$$cAshis K. Mukherjee.
001439243 264_1 $$aSingapore :$$bSpringer,$$c2021.
001439243 300__ $$a1 online resource
001439243 336__ $$atext$$btxt$$2rdacontent
001439243 337__ $$acomputer$$bc$$2rdamedia
001439243 338__ $$aonline resource$$bcr$$2rdacarrier
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001439243 347__ $$bPDF
001439243 504__ $$aReferences-4: Indian Spectacled Cobra (Naja naja)-4.1 Taxonomic Classification of the Indian Spectacled Cobra (Naja naja)-4.2 Characteristic Features of the Indian Spectacled Cobra-4.3 Geographical Distribution and Reproduction of the Indian Spectacled Cobra-4.4 Biochemical Composition of the Indian Spectacled Cobra Venom-4.5 Biochemical and Proteomic Analyses to Demonstrate the Geographical Differences in Venom Composition of Indian Spectacled C ...-4.6 Genomic and Transcriptomic Analyses of Indian Spectacled Cobra Venom Toxins.
001439243 504__ $$aIncludes bibliographical references.
001439243 5050_ $$aIntro -- Preface -- Contents -- About the Author -- 1: Introduction -- 1.1 A Glimpse of the Venomous Snakes of India -- 1.2 The Concept of the ``Big Four ́́and Non-``Big Four ́́Medically Important Venomous Snakes of India -- 1.3 Medical Aspects of Snakebite: The Snakebite Problem -- 1.3.1 Snakebite in Developed Countries -- 1.3.2 Epidemiology of Snakebite in Asia -- 1.3.3 Epidemiology of Snakebite in India -- 1.4 Key Issues Pertaining to Snakebite in India -- References -- 2: Evolution of Snakes and Systematics of the ``Big Four ́́Venomous Snakes of India -- 2.1 Evolution of Snakes
001439243 5058_ $$a2.2 Studies of the Genomics, Phenomics, and Fossil Record Show the Origin and Evolution of Snakes -- 2.3 Studies on the Genomic Regression of Claw Keratin, Taste Receptors, and Light-Associated Genes and the Evolutionary Origin... -- 2.4 Skull Evolution and the Ecological Origin of Snakes -- 2.5 Systematics of the ``Big Four ́́Venomous Snakes of India -- 2.6 The ``Big Four ́́Venomous Snakes of India Represent the Advanced Group of Snakes -- 2.6.1 Family Elapidae -- 2.6.1.1 Genus Bungarus (Kraits) -- 2.6.1.2 Genus Naja (Cobras) -- 2.6.2 Family Viperidae -- 2.6.2.1 Genus Daboia
001439243 5058_ $$a2.6.2.2 Genus Echis -- References -- 3: Snake Venom: Composition, Function, and Biomedical Applications -- 3.1 The Venom Gland and Venom Delivery Apparatus in the Viperidae and Elapidae Families of Snakes -- 3.2 Comprehensive Review of the Venom Composition of the ``Big Four ́́Venomous Snakes of India -- 3.2.1 Enzymatic Toxins of the ``Big Four ́́Snake Venoms -- 3.2.2 Nonenzymatic Toxins in the ``Big Four ́́Snake Venoms -- 3.2.3 Nonprotein Components of Snake Venom -- 3.3 Variation in Snake Venom Composition and Its Impact on the Pathogenesis of Snakebite and Antivenom Treatment
001439243 5058_ $$a3.4 Evolution of Genes for the Toxins in Snake Venom -- 3.4.1 Toxicofera Hypothesis -- 3.4.2 Independent Origin Hypothesis -- 3.5 Mechanism of the Evolution and Diversification of Venom Proteins -- 3.5.1 Accelerated Evolution of Venom Protein Genes -- 3.5.2 Selection Pressure for Rapid Adaptive Evolution -- 3.5.3 Diet and Snake Venom Evolution -- 3.6 Biological Functions of Venom -- 3.6.1 Prey-Specific Venom Toxicity -- 3.6.2 Immobilization and Predigestion of Prey -- 3.6.3 Prey Re-localization -- 3.7 Indian Snake Venom Proteins: A Treasure House of Drug Prototypes and Diagnostic Tool
001439243 506__ $$aAccess limited to authorized users.
001439243 520__ $$aThis book provides detailed and updated knowledge about medically important Big Four venomous snakes of India (Indian spectacled cobra, Indian common krait, Indian Russells viper, and Indian saw-scaled viper). This book essentially covers the snakebite problem in the world with particular reference to Asia and India. It discusses the evolution and systematics of venomous snakes, emphasizing Big Four venomous snakes of India; the evolution and composition of venoms determined by traditional biochemical and modern proteomic analyses. It also describes the pharmacological properties of enzymatic and non-enzymatic toxins of Big Four venomous snakes of India. Different chapters discuss exciting topics such as species-specific and geographical differences in venom composition and its impact on pathophysiology and clinical manifestations of snakebite envenomation in India, biomedical application of Indian snake venom toxins; production and quality assessment of commercial antivenom, prevention, and treatment of snakebite in India, adverse effects of antivenom including strategies to combat antivenom reactions inpatient. This book caters to toxinologists, pharmacologists, zoologists, antivenom manufacturers, biochemists, clinicians, evolutionary biologists, herpetologists, and informed non-specialists interested to know about the Indian snake venoms.
001439243 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed September 13, 2021).
001439243 650_0 $$aPoisonous snakes$$xVenom$$zIndia.
001439243 650_0 $$aPoisonous snakes$$zIndia.
001439243 650_6 $$aSerpents venimeux$$xVenin$$zInde.
001439243 650_6 $$aSerpents venimeux$$zInde.
001439243 655_0 $$aElectronic books.
001439243 77608 $$iPrint version:$$aMukherjee, Ashis K.$$t'big four' snakes of India.$$dSingapore : Springer, 2021$$z9811628955$$z9789811628955$$w(OCoLC)1247827561
001439243 852__ $$bebk
001439243 85640 $$3Springer Nature$$uhttps://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-981-16-2896-2$$zOnline Access$$91397441.1
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001439243 980__ $$aEBOOK
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