The hereditary basis of childhood cancer / David Malkin, editor.
Malkin, David (Oncologist), editor.
2021
RC281.C4
Available Online

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Title The hereditary basis of childhood cancer / David Malkin, editor.
ISBN 9783030744489 (electronic bk.)
3030744485 (electronic bk.)
3030744469
9783030744465
DOI https://doi.org/10.1007/978-3-030-74448-9
Publication Details Cham, Switzerland : Springer, 2021.
Language English
Description 1 online resource
Item Number 10.1007/978-3-030-74448-9 doi
Call Number RC281.C4
Dewey Decimal Classification 618.92/994
Summary This volume elaborates on the research and clinical implications of the hereditary and molecular basis of childhood cancers. The focus of the disease-related chapters of the book is to integrate what is known about the molecular basis of that particular clinical entity (or group of related entities) with the clinical manifestations, to relate the relationship of the molecular oncologic pathways with relevant developmental or non-human species biology in order to better understand the complexity of these systems. The resulting clinical implications of understanding this biology are elaborated on. Chapters 13-16 discuss the broader psychosocial, ethical and genetic counseling issues that arise and that are so critical to translating the knowledge gained from advances in molecular genetics into the clinic. Chapter 12 in particular provides a unique perspective of the application of this knowledge in less-developed nations where modern technologies may not be readily available, but where the clinical manifestations of these disorders are prevalent.
Note Includes index.
Access Note Access limited to authorized users.
Digital File Characteristics text file
PDF
Source of Description Online resource; title from PDF title page (SpringerLink, viewed September 24, 2021).
Added Author Malkin, David (Oncologist), editor.
Available in Other Form Hereditary basis of childhood cancer.
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1: Li-Fraumeni Syndrome
2: Pediatric Central Nervous System Cancer Predisposition
3: Rhabdoid Tumors
4: Neurofibromatosis
5: Pheochromocytoma and Paraganglioma syndromes
6: Wilms tumor
7: Hereditary Overgrowth Syndromes
8: Multiple Endocrine Neoplasias and Associated Non-Endocrine Conditions
9: DICER1 Syndrome
10: Cancer-prone Inherited Bone Marrow Failure, Myelodysplastic and Acute Myeloid Leukemia Syndromes
11: Inherited Risk for Childhood Leukemia
12: Inherited pediatric cancer in low and intermediate resource countries
13: Frontline Ethico-legal Issues in Childhood Cancer Genetics Research
14: Genetic counseling and testing
15: Psychosocial aspects of childhood cancer genetics
16: Recognition of cancer predisposition syndromes.

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