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1. Introduction
2. A Review and Challenges in Chemical Master Equation
3. Visualizing Markov Process through Graphs and Trees
4. Intelligent State Projection
5. Comparative Study And Analysis of Methods and Models
6. A Large Model Case Study: Solving CME for G1/S Checkpoint Involving the DNA-damage Signal Transduction Pathway
7. An Integrated Large Model Case Study: Solving CME for Oxidative Stress Adaptation in the Fungal Pathogen Candida Albicans.

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