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001439682 001__ 1439682
001439682 003__ OCoLC
001439682 005__ 20230309004514.0
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001439682 020__ $$a9783030855369$$q(electronic bk.)
001439682 020__ $$a3030855368$$q(electronic bk.)
001439682 020__ $$z9783030855352
001439682 020__ $$z303085535X
001439682 0247_ $$a10.1007/978-3-030-85536-9$$2doi
001439682 035__ $$aSP(OCoLC)1268325517
001439682 040__ $$aYDX$$beng$$erda$$epn$$cYDX$$dGW5XE$$dOCLCO$$dEBLCP$$dOCLCF$$dUKAHL$$dOCLCQ$$dCOM$$dOCLCO$$dOCLCQ
001439682 049__ $$aISEA
001439682 050_4 $$aQP114.C44$$bK37 2021
001439682 08204 $$a612.1/7$$223
001439682 1001_ $$aKartha, C. Chandrasekharan,$$eauthor.
001439682 24510 $$aCardiomyocytes in health and disease /$$cChandrasekharan C. Kartha.
001439682 264_1 $$aCham :$$bSpringer,$$c[2021]
001439682 264_4 $$c©2021
001439682 300__ $$a1 online resource :$$billustrations (chiefly color)
001439682 336__ $$atext$$btxt$$2rdacontent
001439682 337__ $$acomputer$$bc$$2rdamedia
001439682 338__ $$aonline resource$$bcr$$2rdacarrier
001439682 504__ $$aIncludes bibliographical references and index.
001439682 5050_ $$aSection I: Normal Cardiomyocyte and its Growth -- 1. Structure and Function of Cardiomyocyte -- 2. Development of Cardiomyocyte -- 3. Cell Cycle Regulation in Cardiomyocytes -- 4. Cardiac Fibroblast and Cardiomyocyte Growth -- 5. Role of Endocardium and Epicardium in Generation of Cardiomyocytes -- Cardiomyocytes in the Mammalian Adult Heart -- 7. Energy Metabolism in Cardiomyocytes -- Section II: Cardiomyocyte Responses 8. Response of Cardiomyocytes to Mechanical Stress -- Cardiomyocyte Responses to Hormones 10. Sequelae of Genetic Defects in Cardiomyocytes -- 11. Response and Effects of Cardiomyocyte Progenitors in the Infarcted Heart -- Section III: Cardiomyocyte Aging and Death -- 12. Cardiomyocyte Senescence -- 13. Mechanisms of Cardiomyocyte Death -- 14. Cardiomyocyte Response to Ischemic Injury -- 15. Cardiomyocytes in Heart Failure -- Section IV: Cardiomyocyte Regeneration -- 16. Endogenous Mechanisms for Cardiomyocyte Regeneration -- 17. Mechanisms to Induce Cardiomyocyte Proliferation -- 18. Cell Sources of Cardiomyocytes for Heart Repair -- 19. Reprograming Fibroblasts for Cardiomyocytes and Progenitors -- Section V: Translational Aspects of Cardiomyocyte Biology -- 20. Clinical Translation of Discoveries in Cardiomyocyte Biology.
001439682 506__ $$aAccess limited to authorized users.
001439682 520__ $$aThis book is a treatise on cardiomyocytes, the most important cell for the contractile function of the heart. There has been significant progress in our understanding of the function-related structure, developmental processes and their determinants, mechanisms of cell cycle regulation, post-natal growth, energy metabolism, and reversible and irreversible response of cardiomyocytes to diverse forms of physiological stress and injury. There is also more clarity on the alterations in the biological mechanisms in cardiomyocytes that lead to pathological states and the changes in the cells that occur secondary to disease conditions. Thanks to these advances in knowledge, there have been great gains in attempts to identify disease biomarkers and therapeutic targets for better management of patients with heart diseases. Possibilities to induce regeneration or proliferation of cardiomyocytes and thus repair and or regenerate the damaged heart are also on the horizon.
001439682 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed September 29, 2021).
001439682 650_0 $$aHeart cells.
001439682 650_6 $$aCellules cardiaques.
001439682 655_0 $$aElectronic books.
001439682 77608 $$iPrint version:$$aKartha, C. Chandrasekharan.$$tCardiomyocytes in health and disease.$$dCham : Springer, [2021]$$z303085535X$$z9783030855352$$w(OCoLC)1261362084
001439682 852__ $$bebk
001439682 85640 $$3Springer Nature$$uhttps://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-3-030-85536-9$$zOnline Access$$91397441.1
001439682 909CO $$ooai:library.usi.edu:1439682$$pGLOBAL_SET
001439682 980__ $$aBIB
001439682 980__ $$aEBOOK
001439682 982__ $$aEbook
001439682 983__ $$aOnline
001439682 994__ $$a92$$bISE