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1. Introduction: Biomedical Innovation and Policy in the Twenty-First Century
2. The Rise of Genomics and Personalized Medicine
3. Patient Narratives: Personalized Medicine in the Field
4. Alliances: Knowledge Infrastructures, and the Digitization of Precision Health
5. Tumor Genesis and Precision Oncology
6. Trends in Precision Oncology and Precision Medicine 2.0
7. Personalized medicines impact on disease
8. The Genome in the Clinic and Boardroom: Biomarkers, Diagnosis, Treatment, and Education
9. A New Set of Clinical tools for Physicians
10. Legislation, Reimbursement and the Regulatory Landscape
11. Translational personalized medicine: Molecular profiling, druggable targets, and clinical genomic medicine
12. The Health Economics of Personalized Precision Medicine
13. Moral, Societal and Ethical Issues: Claims, Consequences, and Caveats
14. Conclusion.

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