TY - GEN AB - This book comprehensively summarizes the biology, etiology, and pathology of ovarian cancer and explores the role of deep molecular and cellular profiling in the advancement of precision medicine. The initial chapter discusses our current understanding of the origin, development, progression and tumorigenesis of ovarian cancer. In turn, the book highlights the development of resistance, disease occurrence, and poor prognosis that are the hallmarks of ovarian cancer. The book then reviews the role of deep molecular and cellular profiling to overcome challenges that are associated with the treatment of ovarian cancer. It explores the use of genome-wide association analysis to identify genetic variants for the evaluation of ovarian carcinoma risk and prognostic prediction. Lastly, it highlights various diagnostic and prognostic ovarian cancer biomarkers for the development of molecular-targeted therapy. AU - El Bairi, Khalid, CN - RC280.O8 DO - 10.1007/978-981-16-1873-4 DO - doi ID - 1440289 KW - Ovaries KW - Ovaries KW - Biochemical markers. KW - Ovaires KW - Ovaires KW - Marqueurs biologiques. LK - https://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-981-16-1873-4 N2 - This book comprehensively summarizes the biology, etiology, and pathology of ovarian cancer and explores the role of deep molecular and cellular profiling in the advancement of precision medicine. The initial chapter discusses our current understanding of the origin, development, progression and tumorigenesis of ovarian cancer. In turn, the book highlights the development of resistance, disease occurrence, and poor prognosis that are the hallmarks of ovarian cancer. The book then reviews the role of deep molecular and cellular profiling to overcome challenges that are associated with the treatment of ovarian cancer. It explores the use of genome-wide association analysis to identify genetic variants for the evaluation of ovarian carcinoma risk and prognostic prediction. Lastly, it highlights various diagnostic and prognostic ovarian cancer biomarkers for the development of molecular-targeted therapy. SN - 9789811618734 SN - 9811618739 T1 - Ovarian cancer biomarkers :mapping to improve outcomes / TI - Ovarian cancer biomarkers :mapping to improve outcomes / UR - https://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-981-16-1873-4 ER -