Ovarian cancer biomarkers : mapping to improve outcomes / Khalid El Bairi, editor.
El Bairi, Khalid, editor.
2021
RC280.O8 O83 2021
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Title
Ovarian cancer biomarkers : mapping to improve outcomes / Khalid El Bairi, editor.
ISBN
9789811618734 (electronic bk.)
9811618739 (electronic bk.)
9789811618727
9811618720
DOI
https://doi.org/10.1007/978-981-16-1873-4
Published
Singapore : Springer, [2021]
Copyright
©2021
Language
English
Description
1 online resource : illustrations (some color)
Item Number
10.1007/978-981-16-1873-4 doi
Call Number
RC280.O8 O83 2021
Dewey Decimal Classification
616.99/465
Summary
This book comprehensively summarizes the biology, etiology, and pathology of ovarian cancer and explores the role of deep molecular and cellular profiling in the advancement of precision medicine. The initial chapter discusses our current understanding of the origin, development, progression and tumorigenesis of ovarian cancer. In turn, the book highlights the development of resistance, disease occurrence, and poor prognosis that are the hallmarks of ovarian cancer. The book then reviews the role of deep molecular and cellular profiling to overcome challenges that are associated with the treatment of ovarian cancer. It explores the use of genome-wide association analysis to identify genetic variants for the evaluation of ovarian carcinoma risk and prognostic prediction. Lastly, it highlights various diagnostic and prognostic ovarian cancer biomarkers for the development of molecular-targeted therapy.
Access Note
Access limited to authorized users.
Source of Description
Online resource; title from PDF title page (SpringerLink, viewed October 19, 2021).
Added Author
El Bairi, Khalid, editor.
Available in Other Form
Print version: 9789811618727
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Chapter 1. General Overview of the Origins and Pathology of Ovarian Cancer
Chapter 2_An Introduction to the Current Management of Ovarian Cancer in the Era of Precision Oncology
Chapter 3_The Hallmarks of Ovarian Cancer: Actionable Genetics, Targetable Pathways and Predictive Biomarkers
Chapter 4_Genetic Alterations in Ovarian Cancer as Prognostic and Predictive Biomarkers of Therapy Response and Surgical Outcomes
Chapter 5_The Emergence of Circulating Tumor DNA in the Management of Ovarian Cancer
Chapter 6_Proteomic Biomarkers for Early Detection and Patients' Stratification in Ovarian Cancer
Chapter 7_Cutting-edge Technologies and Ovarian Cancer.

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