001440293 000__ 04064cam\a2200637\i\4500 001440293 001__ 1440293 001440293 003__ OCoLC 001440293 005__ 20230309004554.0 001440293 006__ m\\\\\o\\d\\\\\\\\ 001440293 007__ cr\un\nnnunnun 001440293 008__ 211013s2021\\\\sz\a\\\\o\\\\\000\0\eng\d 001440293 019__ $$a1275428844$$a1276778138$$a1276852929 001440293 020__ $$a9783030783112$$q(electronic bk.) 001440293 020__ $$a3030783111$$q(electronic bk.) 001440293 020__ $$z9783030783105 001440293 020__ $$z3030783103 001440293 0247_ $$a10.1007/978-3-030-78311-2$$2doi 001440293 035__ $$aSP(OCoLC)1275356569 001440293 040__ $$aYDX$$beng$$erda$$epn$$cYDX$$dGW5XE$$dEBLCP$$dOCLCF$$dOCLCO$$dOCLCQ$$dCOM$$dOCLCO$$dSFB$$dUKAHL$$dOCLCQ 001440293 049__ $$aISEA 001440293 050_4 $$aRC643$$b.B56 2021 001440293 08204 $$a616.99/419$$223 001440293 24500 $$aBiology and treatment of leukemia and bone marrow neoplasms /$$cVinod Pullarkat, Guido Marcucci, editors. 001440293 264_1 $$aCham :$$bSpringer,$$c[2021] 001440293 264_4 $$c©2021 001440293 300__ $$a1 online resource :$$billustrations (chiefly color) 001440293 336__ $$atext$$btxt$$2rdacontent 001440293 337__ $$acomputer$$bc$$2rdamedia 001440293 338__ $$aonline resource$$bcr$$2rdacarrier 001440293 4901_ $$aCancer treatment and research,$$x2509-8497 ;$$vvolume 181 001440293 5050_ $$aAdvances in diagnosis and risk stratification of leukemias and bone marrow neoplasms -- Genetics and diagnostic approach to lymphoblastic leukemia -- Acute promyelocytic leukemia: update on risk stratification and treatment -- Current and emerging therapies for AML -- Current management and new developments in treatment of ALL -- Contemporary therapy of CML -- MDS: Pathogenesis and therapy -- Chronic lymphocytic leukemia: Biology and therapy -- Biology and current treatment of Myeloproliferative neoplasms -- Systemic Mastocytosis: Pathology and treatment -- Adoptive T-cell therapy and other novel immunotherapies for leukemia. 001440293 506__ $$aAccess limited to authorized users. 001440293 520__ $$aThis book provides a concise update on current understanding of the biology of acute and chronic leukemias and other bone marrow neoplasms, including myelodysplastic and myeloproliferative disorders, and explores new and emerging treatments. There is a particular focus on the molecular abnormalities that are drivers of leukemia and on their detection by modern molecular techniques. Knowledge of the ways in which genomic and metabolic abnormalities in the hematologic neoplasms affect prognosis and treatment decision making is reviewed. Detailed attention is devoted to targeted therapies, including novel drugs, and to potential targets for future drug development. In addition, readers find in-depth discussion of cellular and antibody-based immunotherapies as well as the role of hematopoietic stem cell transplantation in the treatment of leukemias and bone marrow malignancies. The book is of special interest for hematologists, oncologists, and cancer researchers; it is also of value for hematology trainees and medical students. 001440293 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed October 18, 2021). 001440293 650_0 $$aAcute leukemia. 001440293 650_0 $$aAcute leukemia$$xTreatment. 001440293 650_0 $$aChronic leukemia. 001440293 650_0 $$aChronic leukemia$$xTreatment. 001440293 650_0 $$aBone marrow$$xTumors. 001440293 650_0 $$aBone marrow$$xTumors$$xTreatment. 001440293 650_6 $$aLeucémie aiguë. 001440293 650_6 $$aLeucémie aiguë$$xTraitement. 001440293 650_6 $$aMoelle osseuse$$xTumeurs. 001440293 650_6 $$aMoelle osseuse$$xTumeurs$$xTraitement. 001440293 655_7 $$aLlibres electrònics.$$2thub 001440293 655_0 $$aElectronic books. 001440293 7001_ $$aPullarkat, Vinod,$$eeditor. 001440293 7001_ $$aMarcucci, Guido,$$eeditor. 001440293 77608 $$iPrint version:$$tBiology and treatment of leukemia and bone marrow neoplasms.$$dCham : Springer, [2021]$$z3030783103$$z9783030783105$$w(OCoLC)1250310908 001440293 830_0 $$aCancer treatment and research ;$$vv. 181.$$x2509-8497 001440293 852__ $$bebk 001440293 85640 $$3Springer Nature$$uhttps://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-3-030-78311-2$$zOnline Access$$91397441.1 001440293 909CO $$ooai:library.usi.edu:1440293$$pGLOBAL_SET 001440293 980__ $$aBIB 001440293 980__ $$aEBOOK 001440293 982__ $$aEbook 001440293 983__ $$aOnline 001440293 994__ $$a92$$bISE