Hereditary breast and ovarian cancer : molecular mechanism and clinical practice / Seigo Nakamura, Daisuke Aoki, Yoshio Miki, editors.
Nakamura, Seigo, editor.; Aoki, Daisuke, editor.; Miki, Yoshio, editor.
2021
RC280.B8
Available Online

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Details

Title
Hereditary breast and ovarian cancer : molecular mechanism and clinical practice / Seigo Nakamura, Daisuke Aoki, Yoshio Miki, editors.
ISBN
9789811645211 (electronic bk.)
9811645213 (electronic bk.)
9811645205
9789811645204
DOI
https://doi.org/10.1007/978-981-16-4521-1
Publication Details
Singapore : Springer, 2021.
Language
English
Description
1 online resource
Item Number
10.1007/978-981-16-4521-1 doi
Call Number
RC280.B8
Dewey Decimal Classification
616.99/449042
Summary
This highly informative and clearly written book presents the basic science and the latest data on hereditary breast and ovarian cancer (HBOC) to provide an up-to-date and holistic overview of the disease. It starts off by presenting the molecular mechanisms, genetic testing and counseling, and variants of unknown significance (VUS) to help readers understand the contemporary interpretation of the disease. Further chapters focus on the surveillance, diagnosis and treatment, including chemoprevention, risk reduction and drug development based on molecular mechanisms. It also includes a chapter on the latest findings from the HBOC database, ethical issues and the parp inhibitors, and discusses innovative thinking to manage and understand the disease. Hereditary Breast and Ovarian Cancer - Molecular Mechanism and Clinical Practice offers breast surgeons, medical oncologists, gynecological oncologists and genetic counselors a comprehensive overview of the disease. Providing insights into recent scientific findings and further avenues for investigation, it is also a thought-provoking and informative read for researchers and scholars.
Access Note
Access limited to authorized users.
Digital File Characteristics
text file
PDF
Source of Description
Online resource; title from PDF title page (SpringerLink, viewed November 4, 2021).
Added Author
Nakamura, Seigo, editor.
Aoki, Daisuke, editor.
Miki, Yoshio, editor.
Available in Other Form
Hereditary breast and ovarian cancer.
Linked Resources
Online Access
Record Appears in
Online Resources > Ebooks
All Resources
1 History, Advancements, and Future Strategies
2 Molecular basis of BRCA1 and BRCA2
Homologous recombination deficiency and tissue-specific carcinogenesis
3 Genetic Testing
4 Variants of uncertain significances in hereditary breast and ovarian cancer
5 Genetic counseling in Hereditary Breast and Ovarian Cancer
6 Hereditary Breast Cancer
7 Hereditary Ovarian Cancer
8 Risk-Based Breast Cancer Screening
9 Chemoprevention for Breast Cancer
10 Chemoprevention for Ovarian Cancer
11 Risk-Reducing Mastectomy (RRM)
12 Risk-reducing salpingo-oophorectomy (RRSO)
13 Panel Testing
14 Germline Findings through Precision Oncology for Ovarian Cancer
15 Germline Findings from Genetic Testing for Breast Cancer
16 Hereditary Breast and Ovarian Cancer (HBOC) Database
17 Ethical Issues: Overview in Genomic analysis and Clinical Context
18 PARP Inhibitors-Mechanism of action
19 PARPi
Efficacy in Hereditary Breast Cancer
20 Efficacy of Poly ADP-Ribose Polymerase Inhibitors for Hereditary Ovarian Cancer.

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