@article{1440492,
      recid = {1440492},
      author = {Powell, Lynda H., and Freedland, Kenneth E., and Kaufmann,  Peter G.,},
      title = {Behavioral clinical trials for chronic diseases :  scientific foundations /},
      pages = {1 online resource (1 volume) :},
      abstract = {This is the first comprehensive guide to the design of  behavioral randomized clinical trials (RCT) for chronic  diseases. It includes the scientific foundations for  behavioral trial methods, problems that have been  encountered in past behavioral trials, advances in design  that have evolved, and promising trends and opportunities  for the future. The value of this book lies in its  potential to foster an ability to speak the language of  medicine through the conduct of high-quality behavioral  clinical trials that match the rigor commonly seen in  double-blind drug trials. It is relevant for testing any  treatment aimed at improving a behavioral, social,  psychosocial, environmental, or policy-level risk factor  for a chronic disease including, for example, obesity,  sedentary behavior, adherence to treatment, psychosocial  stress, food deserts, and fragmented care. Outcomes of  interest are those that are of clinical significance in the  treatment of chronic diseases, including standard risk  factors such as cholesterol, blood pressure, and glucose,  and clinical outcomes such as hospitalizations, functional  limitations, excess morbidity, quality of life, and  mortality. This link between behavior and chronic disease  requires innovative clinical trial methods not only from  the behavioral sciences but also from medicine,  epidemiology, and biostatistics. This integration does not  exist in any current book, or in any training program, in  either the behavioral sciences or medicine.},
      url = {http://library.usi.edu/record/1440492},
      doi = {https://doi.org/10.1007/978-3-030-39330-4},
}