001440492 000__ 04128cam\a2200541\i\4500 001440492 001__ 1440492 001440492 003__ OCoLC 001440492 005__ 20230309004607.0 001440492 006__ m\\\\\o\\d\\\\\\\\ 001440492 007__ cr\cn\nnnunnun 001440492 008__ 211026s2021\\\\sz\a\\\\o\\\\\000\0\eng\d 001440492 019__ $$a1276847939$$a1276933558$$a1277011355 001440492 020__ $$a9783030393304$$q(electronic bk.) 001440492 020__ $$a3030393305$$q(electronic bk.) 001440492 020__ $$z9783030393281 001440492 020__ $$z3030393283 001440492 0247_ $$a10.1007/978-3-030-39330-4$$2doi 001440492 035__ $$aSP(OCoLC)1280404056 001440492 040__ $$aGW5XE$$beng$$erda$$epn$$cGW5XE$$dYDX$$dEBLCP$$dOCLCF$$dSFB$$dOCLCO$$dOCLCQ$$dOCLCO$$dN$T$$dUKAHL$$dOCLCQ 001440492 049__ $$aISEA 001440492 050_4 $$aRC108 001440492 08204 $$a616/.044$$223 001440492 1001_ $$aPowell, Lynda H.,$$eauthor. 001440492 24510 $$aBehavioral clinical trials for chronic diseases :$$bscientific foundations /$$cLynda H. Powell, Kenneth E. Freedland, Peter G. Kaufmann. 001440492 264_1 $$aCham :$$bSpringer,$$c2021. 001440492 300__ $$a1 online resource (1 volume) :$$billustrations (black and white, and color) 001440492 336__ $$atext$$btxt$$2rdacontent 001440492 337__ $$acomputer$$bc$$2rdamedia 001440492 338__ $$aonline resource$$bcr$$2rdacarrier 001440492 5050_ $$aIntroduction: the window of opportunity -- A selected history of randomized behavioral clinical trials: what we learned -- A clinically significant problem and a clincially significant benefit -- The process of developing a behavioral treatment for chronic disease -- The hypothesized pathway from behavioral treatment to chronic disease -- Equipoise, blinding, and investigator discipline -- Sensitivity to diversity -- Protection of randomization -- Choice of appropriate control group -- Readiness to conduct a behavioral randomized clinical trial -- Concluding remarks. 001440492 506__ $$aAccess limited to authorized users. 001440492 520__ $$aThis is the first comprehensive guide to the design of behavioral randomized clinical trials (RCT) for chronic diseases. It includes the scientific foundations for behavioral trial methods, problems that have been encountered in past behavioral trials, advances in design that have evolved, and promising trends and opportunities for the future. The value of this book lies in its potential to foster an ability to speak the language of medicine through the conduct of high-quality behavioral clinical trials that match the rigor commonly seen in double-blind drug trials. It is relevant for testing any treatment aimed at improving a behavioral, social, psychosocial, environmental, or policy-level risk factor for a chronic disease including, for example, obesity, sedentary behavior, adherence to treatment, psychosocial stress, food deserts, and fragmented care. Outcomes of interest are those that are of clinical significance in the treatment of chronic diseases, including standard risk factors such as cholesterol, blood pressure, and glucose, and clinical outcomes such as hospitalizations, functional limitations, excess morbidity, quality of life, and mortality. This link between behavior and chronic disease requires innovative clinical trial methods not only from the behavioral sciences but also from medicine, epidemiology, and biostatistics. This integration does not exist in any current book, or in any training program, in either the behavioral sciences or medicine. 001440492 588__ $$aDescription based on print version record. 001440492 650_0 $$aChronic diseases$$xTreatment$$xResearch. 001440492 650_0 $$aBehavior therapy$$xResearch. 001440492 650_6 $$aMaladies chroniques$$xTraitement$$xRecherche. 001440492 650_6 $$aThérapie de comportement$$xRecherche. 001440492 655_7 $$aLlibres electrònics.$$2thub 001440492 655_0 $$aElectronic books. 001440492 7001_ $$aFreedland, Kenneth E.,$$eauthor. 001440492 7001_ $$aKaufmann, Peter G.,$$eauthor. 001440492 77608 $$iPrint version:$$aPowell, Lynda H.$$tBehavioral clinical trials for chronic diseases.$$dCham : Springer, 2021$$z9783030393281$$w(OCoLC)1255872533 001440492 852__ $$bebk 001440492 85640 $$3Springer Nature$$uhttps://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-3-030-39330-4$$zOnline Access$$91397441.1 001440492 909CO $$ooai:library.usi.edu:1440492$$pGLOBAL_SET 001440492 980__ $$aBIB 001440492 980__ $$aEBOOK 001440492 982__ $$aEbook 001440492 983__ $$aOnline 001440492 994__ $$a92$$bISE