Flow chemistry in drug discovery / Jesus Alcazar, Antonio de la Hoz, Angel Díaz-Ortiz, editors ; with contributions by I. Abdiaj [and 30 others].
Alcazar, Jesus, editor.; Hoz, Antonio de la, editor.; Díaz-Ortiz, Angel, editor.
2021
RM301.25 .F56 2021
Available Online

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Title Flow chemistry in drug discovery / Jesus Alcazar, Antonio de la Hoz, Angel Díaz-Ortiz, editors ; with contributions by I. Abdiaj [and 30 others].
ISBN 9783030855925 (electronic bk.)
3030855929 (electronic bk.)
9783030855918
3030855910
DOI https://doi.org/10.1007/978-3-030-85592-5
Published Cham : Springer, [2021]
Copyright ©2021
Language English
Description 1 online resource (xxvii, 479 pages)
Item Number 10.1007/978-3-030-85592-5 doi
Call Number RM301.25 .F56 2021
Dewey Decimal Classification 615.1/9
Summary This book reviews the challenges and opportunities posed by flow chemistry in drug discovery, and offers a handy reference tool for medicinal chemists interested in the synthesis of biologically active compounds. Prepared by expert contributors, the respective chapters cover not only fundamental methodologies and reactions, such as the application of catalysis, especially biocatalysis and organocatalysis; and non-conventional activation techniques, from photochemistry to electrochemistry; but also the development of new process windows, processes and reactions in drug synthesis. Particular attention is given to automatization and library synthesis, which are of great importance in the pharmaceutical industry. Readers will also find coverage on selected topics of general interest, such as how flow chemistry is contributing to drug discovery R & D in developing countries, and the green character of this enabling technology, for example in the production of raw materials for the pharmaceutical industry from waste. Given its scope, the book appeals to medicinal chemistry researchers working in academia and industry alike, as well as professionals involved in scale-up and drug development.
Access Note Access limited to authorized users.
Digital File Characteristics text file
PDF
Source of Description Online resource; title from PDF title page (SpringerLink, viewed December 28, 2021).
Added Author Alcazar, Jesus, editor.
Hoz, Antonio de la, editor.
Díaz-Ortiz, Angel, editor.
Series Topics in medicinal chemistry (Springer (Firm)) ; v. 38.
Available in Other Form Flow chemistry in drug discovery.
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Record Appears in Online Resources > Ebooks
All Resources
Flow Chemistry in Drug Discovery: Challenges and Opportunities / Enol López and Jesús Alcázar
Green Aspects of Flow Chemistry for Drug Discovery / Ángel Díaz-Ortiz and Antonio de la Hoz
Photochemistry in Flow for Drug Discovery / Thomas H. Rehm
Electrochemistry in Flow for Drug Discovery / Bethan Winterson and Thomas Wirth
Recent Advances of Asymmetric Catalysis in Flow for Drug Discovery / Yuki Saito and Shu Kobayashi
Multiple Organolithium Reactions for Drug Discovery Using Flash Chemistry / Yosuke Ashikari, Takashi Tamaki, Masahiro Takumi, and Aiichiro Nagaki
Organocatalysis in Continuous Flow for Drug Discovery / Laura Amenós, Esther Alza, and Miquel A. Pericàs
Biocatalysis in Flow for Drug Discovery / Itziar Peñafiel and Sebastian C. Cosgrove
Improved Synthesis of Bioactive Molecules Through Flow Chemistry / Aline Aparecida Nunes de Souza, Elida Betania Ariza Paez, Francisco Fávaro de Assis, Timothy John Brocksom, and Kleber Thiago de Oliveira
New Biomass Reagents for the Synthesis of Bioactive Compounds / Karen Fox, Rafael Luque, Luiz Antonio Soares Romeiro, and Maria Laura Bolognesi
Flow Chemistry Supporting Access to Drugs in Developing Countries / Cloudius R. Sagandira and Paul Watts
Drug Discovery Automation and Library Synthesis in Flow / Paul Richardson and Irini Abdiaj.

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