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1. Introduction
PART I: DEFINITIONS AND BELIEFS
2. Principle of Hot and Cold and its Clinical Application in Traditional Chinese Medicine
3. Principle of Hot and Cold and its Clinical Application in Persian Medicine
4. Principle of Hot (Ushna) and Cold (Sheeta) and its Clinical Application in Ayurvedic Medicine
5. Principle of Hot and Cold and its Clinical Application in Latin American and Caribbean Medicines
PART II: SCIENTIFIC EVIDENCE
6. Hot and Cold Theory: Evidence in Nutrition
7. Hot and Cold Theory: Evidence in Pharmacology
8. Hot and Cold Theory: Evidence in Physiology
9. Hot and Cold Theory: Evidence in Systems Biology
PART III: PERSPECTIVE
10. Hot and Cold Theory: A Personalized Medicine Approach
11. Hot and Cold Theory: Future Perspective.

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