001441852 000__ 04121cam\a2200469Ia\4500 001441852 001__ 1441852 001441852 003__ OCoLC 001441852 005__ 20230309003346.0 001441852 006__ m\\\\\o\\d\\\\\\\\ 001441852 007__ cr\un\nnnunnun 001441852 008__ 220211s2021\\\\si\\\\\\o\\\\\000\0\eng\d 001441852 019__ $$a1296408488$$a1296530967$$a1298394551 001441852 020__ $$a9789811642548$$q(electronic bk.) 001441852 020__ $$a9811642540$$q(electronic bk.) 001441852 020__ $$z9811642532 001441852 020__ $$z9789811642531 001441852 0247_ $$a10.1007/978-981-16-4254-8$$2doi 001441852 035__ $$aSP(OCoLC)1296418791 001441852 040__ $$aYDX$$beng$$cYDX$$dGW5XE$$dEBLCP$$dOCLCO$$dOCLCF$$dOCLCO$$dOCLCQ 001441852 049__ $$aISEA 001441852 050_4 $$aQH603.I54 001441852 08204 $$a571.6/4$$223 001441852 24500 $$aIon channels in biophysics and physiology /$$cLei Zhou, editor. 001441852 260__ $$aSingapore :$$bSpringer,$$c2021. 001441852 300__ $$a1 online resource 001441852 4901_ $$aAdvances in experimental medicine and biology,$$x2214-8019 ;$$vvolume 1349 001441852 5050_ $$aAdvancing ion channel research with automated patch clamp (APC) electrophysiology platforms -- Methods & Challenges to Study Mechanosensitive Ion Channels -- The Polysite Pharmacology of TREK K2P channels -- Physiological functions, biophysical properties and regulation of KCNQ1 (KV7.1) potassium channels -- Context matters Calcium channel splice variants and their effects in brain and cardiovascular function -- Structure-function of TMEM16 ion channels and lipid scramblases -- Distribution and Assembly of TRP Ion Channels -- Regulation of Ion Channel Function by Gas Molecules -- DEG/ENaC ion channels in the function of the nervous system: from worm to man -- Glial chloride channels in the function of the nervous system across species -- Physiological and pathological relevance of selective and non-selective Ca2+ channels in skeletal and cardiac muscle -- Lysosomal TRPML1 Channel: Implications in Cardiovascular and Kidney Diseases -- Store-Operated Calcium Entry in the Cardiovascular System -- The role of thermosensitive ion channels in mammalian thermoregulation -- Mechanotransduction ion channels in hearing and touch -- The functional properties, physiological roles, channelopathy and pharmacological characteristics of the Slack (KCNT1) channel -- Ion Channels in Anesthesiology. 001441852 506__ $$aAccess limited to authorized users. 001441852 520__ $$aThis book gathers relatively recent and significant topics in the field of ion channel research. Ion channels form the molecular basis for membrane excitability in cells from the cardiovascular and nervous systems. In many non-excitable cells, ion channels contribute to diverse function including secretion of signaling compounds like hormones and insulin, cell volume regulation, intracellular signaling especially Ca2+ signaling, etc. Many human diseases have been attributed to abnormal channel functions and defective membrane expression of channel proteins. On the other hand, ion channels are excellent models for studying protein biophysics, especially the allosteric regulation of protein function by miscellaneous stimuli. Therefore, researches on ion channels carry significant meaning for the understanding of basic protein biophysics and diverse physiological functions and for developing novel and effective treatment for related human diseases. This book could provide graduates and scientists in both basic and clinical levels, a comprehensive understanding of cutting-edge advances and a useful and stimulating platform for tackling their own questions about ion channels. 001441852 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed February 22, 2022). 001441852 650_0 $$aIon channels. 001441852 650_6 $$aCanaux ioniques. 001441852 655_0 $$aElectronic books. 001441852 7001_ $$aZhou, Lei,$$eeditor. 001441852 77608 $$iPrint version: $$z9811642532$$z9789811642531$$w(OCoLC)1258071912 001441852 830_0 $$aAdvances in experimental medicine and biology ;$$vv. 1349.$$x2214-8019 001441852 852__ $$bebk 001441852 85640 $$3Springer Nature$$uhttps://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-981-16-4254-8$$zOnline Access$$91397441.1 001441852 909CO $$ooai:library.usi.edu:1441852$$pGLOBAL_SET 001441852 980__ $$aBIB 001441852 980__ $$aEBOOK 001441852 982__ $$aEbook 001441852 983__ $$aOnline 001441852 994__ $$a92$$bISE