001442426 000__ 04508cam\a2200565\i\4500 001442426 001__ 1442426 001442426 003__ OCoLC 001442426 005__ 20230310003418.0 001442426 006__ m\\\\\o\\d\\\\\\\\ 001442426 007__ cr\cn\nnnunnun 001442426 008__ 211014s2022\\\\sz\a\\\\o\\\\\000\0\eng\d 001442426 019__ $$a1287776526 001442426 020__ $$a9783030794859$$q(electronic bk.) 001442426 020__ $$a3030794857$$q(electronic bk.) 001442426 020__ $$z9783030794842 001442426 0247_ $$a10.1007/978-3-030-79485-9$$2doi 001442426 035__ $$aSP(OCoLC)1275778079 001442426 040__ $$aGW5XE$$beng$$erda$$epn$$cGW5XE$$dOCLCF$$dDCT$$dOCLCO$$dOCLCQ$$dN$T$$dOCLCQ$$dCASUM 001442426 049__ $$aISEA 001442426 050_4 $$aRC931.O67$$bE37 2022 001442426 08204 $$a616.7/223$$223 001442426 24500 $$aEarly osteoarthritis :$$bstate-of-the-art approaches to diagnosis, treatment and controversies /$$cChristian Lattermann, Henning Madry, Norimasa Nakamura, Elizaveta Kon, editors. 001442426 264_1 $$aCham :$$bSpringer,$$c[2022] 001442426 264_4 $$c©2022 001442426 300__ $$a1 online resource (ix, 343 pages) :$$billustrations (chiefly color) 001442426 336__ $$atext$$btxt$$2rdacontent 001442426 337__ $$acomputer$$bc$$2rdamedia 001442426 338__ $$aonline resource$$bcr$$2rdacarrier 001442426 347__ $$atext file 001442426 347__ $$bPDF 001442426 5050_ $$aI Definition and Epidemiology -- 1 Definition of "early Osteoarthritis" -- 2 Early signs of OA in x-rays -- 3 MRI measures of early OA -- the ACL-OA score -- 4 Relaxometrie as early measure of OA -- 5 Epidemiology of Osteoarthritis and the importance of early onset-Katz (or delegate) -- 6 Economic aspects of early OA -- 7 Frequency, Epidemiology and Cost of ACL injuries -- 8 The human ACL injury model of early OA -- 9 The risk of early OA after joint fracture -- 10 The clinical manifestation of early OA -- II Basic science aspects of the disease process -- 11 Biomechanics of instability and its relationship to OA -- 12 Fluid dynamics and rheology in the arthritic joint -- 13 How does articular cartilage actually break down? -- 14 Early OA after tibial plateau fracture in the rat -- 15 Matrix degradation after injury -- 16 Collagen breakdown in hip and knee joint over time -- 17 Inflammation after ACL injury -- 18 The role of the "Inflammatype" -- 19 Immune response and early OA -- 20 Macrophages in early OA -- 21 Vesicles and MSC's -- III Clinical Treatment of early OA (non-op) -- 22 Early clinical manifestations of early OA -- 23 When is a chondral defect relevant? -- 24 Role of cortisone in the treatment of early OA -- 25 Viscosupplementation in early OA -- 26 The role of PRP in early OA -- 27 What is the current role and promise of stem cell therapy in early OA -- 28 Role of iPS cells for OA? -- 29 Fat derived stem cells -- 30 BMAC -- IV Clinical Treatment of early OA (operative) -- 30 The role of alignment in the treatment of early OA -- 31 Meniscus injury and early OA, when to operate, when to repair, when to resect? -- 32 Role of arthroscopic debridement, microfracture or washouts -- 33 Osteochondral allograft for early OA -- 34 Cell based procedures for early OA -- 35 Chondral defect repair using a coral based implant -- 36 Options for Early Osteoarthritis treatment in the Shoulder. 001442426 506__ $$aAccess limited to authorized users. 001442426 520__ $$aEarly osteoarthritis is novel topic for orthopedic surgeons and its process begins immediately after joint injury. The mechanical restoration of the joint surface or ligamentous stability is not sufficient to restore the homeostatic environment in the joint, and this leads to osteoarthritis, despite mechanical stability and alignment. This book sheds light on the various mechanisms and systems involved in the gradual decline of the injured joint toward manifest osteoarthritis. Published in collaboration with ISAKOS, this volume appeals to all stakeholders in surgical orthopaedics and sports medicine. 001442426 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed October 14, 2021). 001442426 650_0 $$aOsteoarthritis. 001442426 650_6 $$aArthrose. 001442426 655_0 $$aElectronic books. 001442426 7001_ $$aLattermann, Christian,$$eeditor. 001442426 7001_ $$aMadry, Henning,$$eeditor. 001442426 7001_ $$aNakamura, Norimasa,$$eeditor. 001442426 7001_ $$aKon, Elizaveta,$$eeditor. 001442426 77608 $$iPrint version:$$z9783030794842 001442426 77608 $$iPrint version:$$z9783030794866 001442426 77608 $$iPrint version:$$z9783030794873 001442426 852__ $$bebk 001442426 85640 $$3Springer Nature$$uhttps://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-3-030-79485-9$$zOnline Access$$91397441.1 001442426 909CO $$ooai:library.usi.edu:1442426$$pGLOBAL_SET 001442426 980__ $$aBIB 001442426 980__ $$aEBOOK 001442426 982__ $$aEbook 001442426 983__ $$aOnline 001442426 994__ $$a92$$bISE