TY - GEN AB - This book presents the evidence related to the use of injectable biologics to provide faster and better healing for musculoskeletal lesions and conditions. The authors discuss approaches, such as blood derivatives and cell concentrates, applied to lesions of muscles, ligaments, tendons, bones, meniscus and cartilage, as well as osteoarthritis. Chapters are written by some of the most influential opinion leaders in the field, with up-to-date review of the current literature, where the authors explore both the potential and the limitations of these minimally invasive and promising treatments. The first section is devoted to the formulations and rationale for the use of injectable orthobiologics, while the second section reviews current treatment methods applied to specific joints and pathologies ranging from tendinopathies through non-unions to articular degenerative processes as well as the results of these treatment approaches. The third section explores future perspectives, such as pluripotent stem cells, gene therapy, and the stimulation of intrinsic stromal cell niches. Appealing to a broad readership, this book will be of interest to both laboratory research scientists and clinicians, including orthopedists, sports physicians, physiatrists, and regenerative medicine experts. AU - Filardo, Giuseppe, AU - Mandelbaum, Bert, AU - Muschler, George F., AU - Rodeo, Scott A., AU - Nakamura, Norimasa, CN - RC925 CY - Cham, Switzerland : DA - [2022] DO - 10.1007/978-3-030-84744-9 DO - doi ID - 1443068 KW - Musculoskeletal system KW - Musculoskeletal system KW - Biologicals. KW - Stem cells KW - Appareil locomoteur KW - Appareil locomoteur KW - Produits biologiques. KW - Cellules souches LK - https://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-3-030-84744-9 N2 - This book presents the evidence related to the use of injectable biologics to provide faster and better healing for musculoskeletal lesions and conditions. The authors discuss approaches, such as blood derivatives and cell concentrates, applied to lesions of muscles, ligaments, tendons, bones, meniscus and cartilage, as well as osteoarthritis. Chapters are written by some of the most influential opinion leaders in the field, with up-to-date review of the current literature, where the authors explore both the potential and the limitations of these minimally invasive and promising treatments. The first section is devoted to the formulations and rationale for the use of injectable orthobiologics, while the second section reviews current treatment methods applied to specific joints and pathologies ranging from tendinopathies through non-unions to articular degenerative processes as well as the results of these treatment approaches. The third section explores future perspectives, such as pluripotent stem cells, gene therapy, and the stimulation of intrinsic stromal cell niches. Appealing to a broad readership, this book will be of interest to both laboratory research scientists and clinicians, including orthopedists, sports physicians, physiatrists, and regenerative medicine experts. PB - Springer, PP - Cham, Switzerland : PY - [2022] SN - 9783030847449 SN - 3030847446 T1 - Orthobiologics :injectable therapies for the musculoskeletal system / TI - Orthobiologics :injectable therapies for the musculoskeletal system / UR - https://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-3-030-84744-9 ER -