001443068 000__ 05715cam\a2200625\a\4500
001443068 001__ 1443068
001443068 003__ OCoLC
001443068 005__ 20230310003525.0
001443068 006__ m\\\\\o\\d\\\\\\\\
001443068 007__ cr\un\nnnunnun
001443068 008__ 211206s2022\\\\sz\\\\\\o\\\\\000\0\eng\d
001443068 019__ $$a1287673700$$a1287895523$$a1287923712$$a1294350831$$a1296667146
001443068 020__ $$a9783030847449$$q(electronic bk.)
001443068 020__ $$a3030847446$$q(electronic bk.)
001443068 020__ $$z3030847438
001443068 020__ $$z9783030847432
001443068 0247_ $$a10.1007/978-3-030-84744-9$$2doi
001443068 035__ $$aSP(OCoLC)1287617124
001443068 040__ $$aYDX$$beng$$epn$$cYDX$$dGW5XE$$dOCLCF$$dOCLCO$$dDCT$$dDKU$$dOCLCO$$dOCLCQ$$dN$T$$dOCLCQ
001443068 049__ $$aISEA
001443068 050_4 $$aRC925
001443068 08204 $$a616.7/06$$223
001443068 24500 $$aOrthobiologics :$$binjectable therapies for the musculoskeletal system /$$cGiuseppe Filardo, Bert R. Mandelbaum, George F. Muschler, Scott A. Rodeo, Norimasa Nakamura, editors.
001443068 260__ $$aCham, Switzerland :$$bSpringer,$$c[2022]
001443068 300__ $$a1 online resource
001443068 336__ $$atext$$btxt$$2rdacontent
001443068 337__ $$acomputer$$bc$$2rdamedia
001443068 338__ $$aonline resource$$bcr$$2rdacarrier
001443068 347__ $$atext file
001443068 347__ $$bPDF
001443068 5050_ $$aI. Injectable OrthoBiologics: Formulations and Rationale 1. Bone marrow-derived cultured stromal cells and Bone Marrow Concentrate -- 2. Adipose-derived cultured stromal cells and Stromal Vascular Fraction from adipose tissue -- 3. Synovial-derived cultured stromal cells -- 4. Amniotic, Placenta, and Umbilical cord-derived cultured stromal cells -- 5. Allogeneic cells: pros and cons -- 6. Steroid hormones -- 7. Cytokines, chemokines, alpha-2-macroglobulin, growth factors -- 8. Platelet-rich plasma: leucocyte-rich, leukocyte-poor, autologous conditioned serum, autologous protein solution -- 9. Amniotic tissue extract, placenta tissue extract -- 10. Extracellular vesicles (exosomes) -- II. Injectable OrthoBiolologics: evaluation methods and results based on pathology and anatomy -- 11. Rotator cuff tendinopathy: cell therapy -- 12. Rotator cuff tendinopathy: biologics -- 13. Tennis elbow: cell therapy -- 14. Tennis elbow: cell therapy biologics -- 15. Patellar tendinopathy: cell therapy -- 16. Patellar tendinopathy: biologics -- 17. Achilles tendinopathy: cell therapy -- 18. Achilles tendinopathy: biologics -- 19. Plantar Fasciitis: cell therapy -- 20. Plantar Fasciitis: biologics -- 21. Ligament lesions: cell therapy -- 22. Ligament lesions: biologics -- 23. Meniscal lesions: cell therapy -- 24. Meniscal lesions: biologics -- 25. Muscle lesions: cell therapy -- 26. Muscle lesions: biologics -- 27. Fractures (incl. Nonunions): cell therapy -- 28. Fractures (incl. Nonunions): biologics -- 29. Cartilage lesions and Osteoarthritis of the knee: cell therapy -- 30. Cartilage lesions and Osteoarthritis of the knee: biologics -- 31. Cartilage lesions and Osteoarthritis of the hip and ankle: cell therapy -- 32. Cartilage lesions and Osteoarthritis of the hip and ankle: biologics -- III. Future directions 33. Pluripotent stem cells: Embryonic/Fetal stem cells and induced pluripotent stem (iPS) cells -- 34. Gene therapy -- 35. Stimulation of the intrinsic stromal cell niche -- 36 Conclusions.
001443068 506__ $$aAccess limited to authorized users.
001443068 520__ $$aThis book presents the evidence related to the use of injectable biologics to provide faster and better healing for musculoskeletal lesions and conditions. The authors discuss approaches, such as blood derivatives and cell concentrates, applied to lesions of muscles, ligaments, tendons, bones, meniscus and cartilage, as well as osteoarthritis. Chapters are written by some of the most influential opinion leaders in the field, with up-to-date review of the current literature, where the authors explore both the potential and the limitations of these minimally invasive and promising treatments. The first section is devoted to the formulations and rationale for the use of injectable orthobiologics, while the second section reviews current treatment methods applied to specific joints and pathologies ranging from tendinopathies through non-unions to articular degenerative processes as well as the results of these treatment approaches. The third section explores future perspectives, such as pluripotent stem cells, gene therapy, and the stimulation of intrinsic stromal cell niches. Appealing to a broad readership, this book will be of interest to both laboratory research scientists and clinicians, including orthopedists, sports physicians, physiatrists, and regenerative medicine experts.
001443068 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed December 16, 2021).
001443068 650_0 $$aMusculoskeletal system$$xDiseases$$xTreatment.
001443068 650_0 $$aMusculoskeletal system$$xWounds and injuries$$xTreatment.
001443068 650_0 $$aBiologicals.
001443068 650_0 $$aStem cells$$xTherapeutic use.
001443068 650_6 $$aAppareil locomoteur$$xMaladies$$xTraitement.
001443068 650_6 $$aAppareil locomoteur$$xLésions et blessures$$xTraitement.
001443068 650_6 $$aProduits biologiques.
001443068 650_6 $$aCellules souches$$xEmploi en thérapeutique.
001443068 655_0 $$aElectronic books.
001443068 7001_ $$aFilardo, Giuseppe,$$eeditor.
001443068 7001_ $$aMandelbaum, Bert,$$eeditor.
001443068 7001_ $$aMuschler, George F.,$$eeditor.
001443068 7001_ $$aRodeo, Scott A.,$$eeditor.
001443068 7001_ $$aNakamura, Norimasa,$$eeditor.
001443068 77608 $$iPrint version:$$tOrthobiologics.$$dCham, Switzerland : Springer, [2022]$$z3030847438$$z9783030847432$$w(OCoLC)1260132717
001443068 852__ $$bebk
001443068 85640 $$3Springer Nature$$uhttps://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-3-030-84744-9$$zOnline Access$$91397441.1
001443068 909CO $$ooai:library.usi.edu:1443068$$pGLOBAL_SET
001443068 980__ $$aBIB
001443068 980__ $$aEBOOK
001443068 982__ $$aEbook
001443068 983__ $$aOnline
001443068 994__ $$a92$$bISE