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Introduction
Epidemiology and Impact of CRS
Genetics and Epigenetics of CRS
Mechanisms
Phenotypes of CRS
Endotypes of CRS
Co-morbidities of CRS
Diagnosis
Associated Auto-Immune Disorders
Pediatric CRS
Differential Diagnosis
Medical Treatment
Surgical Approaches
Innovative Treatments and Management
Unmet Needs, Future Directions for Investigation and Innovation.

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