@article{1443657,
      note = {"Doctoral thesis accepted by University of Science and  Technology of China, Hefei, China."},
      author = {Zhang, Yunjiao,},
      url = {http://library.usi.edu/record/1443657},
      title = {Tuning autophagy-inducing activity and toxicity for  lanthanide nanocrystals /},
      abstract = {This thesis presents a simple, yet highly effective  surface engineering solution that uses non-covalent binding  peptides to control the autophagy-inducing activity of  nanomaterials and nanodevices. The author presents RE-1, a  short synthetic peptide that sequence-specifically binds to  lanthanide (LN) oxide and upconversion nanocrystals with  high affinity, which was discovered using an innovative  phage display approach. RE-1 effectively inhibits the  autophagy-inducing activity and toxicity of these  nanocrystals by forming a stable coating layer on the  surface of the nanoparticles, and by reducing their  sedimentation and cell interaction. RE- 1 and its variants  provide a versatile tool for tuning cell interactions in  order to achieve the desired level of autophagic response  and are useful for the various diagnostic and therapeutic  applications of LN-based nanomaterials and nanodevices.},
      doi = {https://doi.org/10.1007/978-981-16-8166-0},
      recid = {1443657},
      pages = {1 online resource (xv, 156 pages) :},
}