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001444032 019__ $$a1294429772$$a1294457188$$a1295270796$$a1296667130
001444032 020__ $$a9783030896010$$q(electronic bk.)
001444032 020__ $$a3030896013$$q(electronic bk.)
001444032 020__ $$z3030896005
001444032 020__ $$z9783030896003
001444032 0247_ $$a10.1007/978-3-030-89601-0$$2doi
001444032 035__ $$aSP(OCoLC)1294344523
001444032 040__ $$aYDX$$beng$$cYDX$$dEBLCP$$dGW5XE$$dDKU$$dN$T$$dOCLCO$$dOCLCF$$dOCLCO$$dUKAHL$$dOCLCQ
001444032 049__ $$aISEA
001444032 050_4 $$aRA652.5
001444032 08204 $$a614.4$$223
001444032 24500 $$aPrinciples of genetics and molecular epidemiology /$$cJuan Carlos Gomez-Verjan, Nadia Alejandra Rivero-Segura, editors.
001444032 260__ $$aCham, Switzerland :$$bSpringer,$$c2022.
001444032 300__ $$a1 online resource
001444032 336__ $$atext$$btxt$$2rdacontent
001444032 337__ $$acomputer$$bc$$2rdamedia
001444032 338__ $$aonline resource$$bcr$$2rdacarrier
001444032 347__ $$atext file$$bPDF$$2rda
001444032 500__ $$aIncludes index.
001444032 504__ $$aReferences -- 2: Molecular Tools for Modern Epidemiology: From the Concepts to Clinical Applications -- Introduction -- PCR -- Types of PCR -- Multiplex PCR -- Real-Time PCR -- Reverse Transcription PCR -- Digital PCR -- Lamp -- Principles of Karyotyping -- FISH -- Microarray -- Immunoassays -- Enzyme-Linked Immunosorbent Assay (ELISA) -- Direct ELISA (Antigen-Coated Plate, Screening Antibody) -- Indirect ELISA (Antigen-Coated Plate -- Screening Antigen/Antibody) -- Sandwich ELISA (Antibody-Coated Plate -- Screening Antigen) -- Competitive ELISA (Screening Antibody) -- New Methods.
001444032 5050_ $$aIntro -- Foreword -- References -- Preface -- Acknowledgements -- Contents -- Contributors -- 1: Principles of Modern Epidemiology and Public Health -- Introduction -- Life-Course Epidemiology -- Principles of Life-Course Research -- Development over Time -- Time and Place -- Timing -- Linked Lives -- Free Will or Agency -- Challenges for Life-Course Epidemiology -- Translational Epidemiology -- Postmodern Epidemiology -- Need for a Refocus on Postmodern Epidemiology -- Analysis Levels to be Considered in Postmodern Epidemiology -- Postmodern Epidemiology Perspective -- Final Considerations
001444032 5058_ $$aClinical Significance -- Western Blot -- Multiplex Western Blot (MWB) -- Capillary Electrophoresis (CE) and Capillary Western Blotting (CWB) -- Microfluidic Western Blotting -- Single-Cell Western Blotting -- Dot Blot -- Far-Western Blotting -- Clinical Significance -- Flow Cytometry -- Clinical Applications -- Phenotypic Characterization of Blood Cells -- Intracellular Antigen Expression -- Characterization of Antigen-Specific Responses -- Cell Cycle Analysis -- Apoptosis -- Proteomics -- Studying the Proteome -- Concluding Remarks -- References -- 3: Genomic Tools in Clinical Epidemiology
001444032 5058_ $$aIntroduction -- NGS in the Study of Relevant SNVs and SNPs for Epidemiological Surveillance -- Implication of NGS Technologies on the Control of SARS-CoV-2 Pandemic -- The Influence of Genomic Tools on the Management of Helicobacter pylori Infection -- General Applications of NGS Technologies in Oncology Practices -- Advances on the Pathogenesis and Treatment Knowledge of Rheumatoid Arthritis by Using NGS -- Concluding Remarks -- References -- 4: Epigenetics in Epidemiology -- Introduction -- Epigenetic Process -- Epigenetic Technology Analysis -- Overview of Bioinformatic Analysis of Epigenome
001444032 5058_ $$aEpigenetic Biomarkers -- Epigenetics in Pharmacology -- Conclusions -- References -- 5: Principles of Clinical Transcriptomics and Splicing -- Introduction -- The Leap From Classic Gene Expression Studies to Transcriptomics -- General Overview of Transcriptomic Technologies -- SAGE-Derived Sequencing Technologies -- Microarrays -- RNA-seq -- Bulk Transcriptomics Profiling and Single-Cell Transcriptomics -- Splicing and Alternative Splicing -- Implications of Alternative Splicing in Clinics -- Applications of Transcriptomics in Clinical Disease -- Concluding Remarks -- References
001444032 506__ $$aAccess limited to authorized users.
001444032 520__ $$aThis book covers some of the most novel genetic and genomic concepts in epidemiology, such as geospatial statistics and systems biology from a clinical point of view by explaining molecular applications with accessible human studies. Featuring a comprehensive table of contents, it includes chapters from genomics and epidemiology surveillance to transcriptomics and alternative splicing principles. Across 17 well-organized chapters, this book meets attempt to explain easily to clinicians and students with basic principles of the genetics, genomics, molecular biology and its applications to epidemiology and public health. The text is distinct from other literature on the market because it covers useful genomic tools applied in epidemiology for clinicians who may not be experts in this branch of health science. Principles of Genetics and Molecular Epidemiology demystifies the idea that biomedicine is far from being applied in both epidemiology and clinical practice.
001444032 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed February 8, 2022).
001444032 650_0 $$aMolecular epidemiology.
001444032 650_0 $$aGenetics.
001444032 650_6 $$aÉpidémiologie moléculaire.
001444032 650_6 $$aGénétique.
001444032 655_0 $$aElectronic books.
001444032 7001_ $$aGomez-Verjan, Juan Carlos,$$eeditor.
001444032 7001_ $$aRivero-Segura, Nadia Alejandra,$$eeditor.
001444032 77608 $$iPrint version:$$z3030896005$$z9783030896003$$w(OCoLC)1269097264
001444032 852__ $$bebk
001444032 85640 $$3Springer Nature$$uhttps://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-3-030-89601-0$$zOnline Access$$91397441.1
001444032 909CO $$ooai:library.usi.edu:1444032$$pGLOBAL_SET
001444032 980__ $$aBIB
001444032 980__ $$aEBOOK
001444032 982__ $$aEbook
001444032 983__ $$aOnline
001444032 994__ $$a92$$bISE