001444635 000__ 03967cam\a2200553Ii\4500 001444635 001__ 1444635 001444635 003__ OCoLC 001444635 005__ 20230310003720.0 001444635 006__ m\\\\\o\\d\\\\\\\\ 001444635 007__ cr\un\nnnunnun 001444635 008__ 220223s2022\\\\sz\a\\\\o\\\\\001\0\eng\d 001444635 019__ $$a1299144763$$a1299275299$$a1299298844 001444635 020__ $$a9783030874513$$q(electronic bk.) 001444635 020__ $$a3030874516$$q(electronic bk.) 001444635 020__ $$z9783030874506 001444635 020__ $$z3030874508 001444635 0247_ $$a10.1007/978-3-030-87451-3$$2doi 001444635 035__ $$aSP(OCoLC)1298936489 001444635 040__ $$aYDX$$beng$$erda$$epn$$cYDX$$dGW5XE$$dEBLCP$$dOCLCO$$dN$T$$dOCLCO$$dUKAHL$$dOCLCQ 001444635 049__ $$aISEA 001444635 050_4 $$aRC382$$b.P37 2022 001444635 08204 $$a616.8/33$$223 001444635 24500 $$aParkinsonism and the environment /$$cNikolay M. Filipov, editor. 001444635 264_1 $$aCham :$$bSpringer,$$c[2022] 001444635 264_4 $$c©2022 001444635 300__ $$a1 online resource :$$billustrations (some color). 001444635 336__ $$atext$$btxt$$2rdacontent 001444635 337__ $$acomputer$$bc$$2rdamedia 001444635 338__ $$aonline resource$$bcr$$2rdacarrier 001444635 4901_ $$aMolecular and integrative toxicology,$$x2168-4235 001444635 500__ $$aIncludes index. 001444635 5050_ $$aExperimental evidence for pesticide contribution in the pathogenesis of Parkinsonism: an update -- Epidemiological evidence for pesticide involvement in the etiology of Parkinson's Disease: current state of affairs? -- Manganese induced Parkinsonism: cellular and molecular mechanisms -- Manganese overexposures in occupational and environmental settings and Parkinsonism: where do we stand -- Aberrant dopamine metabolism as a focal point in the mechanism of environmental contaminant-induced dopaminergic dysfunction -- Emerging contaminants as contributors to Parkinsonism: focus on PhiPs -- Emerging contaminants as contributors to Parkinsonism: focus on PhiPs -- Protein kinase C-delta (PKC-delta): a major molecular target for disparate dopaminergic toxicants -- Environmental contribution to redox dyshomeostasis in Parkinsonism. 001444635 506__ $$aAccess limited to authorized users. 001444635 520__ $$aThe book is comprised of individual reviews with the common goal of providing up-to-date state of the knowledge information on the role the environment plays in the pathogenesis of parkinsonism. The reviews focus on recent advances in the quest of deciphering the molecular and cellular mechanisms of parkinsonian dysfunction, highlight specific emerging dopaminergic toxicants and an alternative experimental model to study the link between environmental exposures and parkinsonism, and provide an update from epidemiological and experimental points of view related to the pesticide exposures and parkinsonism/Parkinson's Disease association. Foremost experts in their respective fields are the senior authors on each chapter and the book fills a critical void that now exists as a book of similar nature has not been published in the last 15 years. Researchers and clinicians with an interest in Parkinson's Disease and related disorders, as well as toxicologists, graduate students, and the general public who are interested in the contribution of environmental factors to neurological dysfunction are among the readership for this book. 001444635 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed February 24, 2022). 001444635 650_0 $$aParkinson's disease$$xEnvironmental aspects. 001444635 650_0 $$aParkinson's disease$$xPathogenesis. 001444635 650_6 $$aMaladie de Parkinson$$xAspect de l'environnement. 001444635 650_6 $$aMaladie de Parkinson$$xPathogenèse. 001444635 655_0 $$aElectronic books. 001444635 7001_ $$aFilipov, Nikolay M.,$$eeditor. 001444635 77608 $$iPrint version:$$z3030874508$$z9783030874506$$w(OCoLC)1264458877 001444635 830_0 $$aMolecular and integrative toxicology.$$x2168-4235 001444635 852__ $$bebk 001444635 85640 $$3Springer Nature$$uhttps://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-3-030-87451-3$$zOnline Access$$91397441.1 001444635 909CO $$ooai:library.usi.edu:1444635$$pGLOBAL_SET 001444635 980__ $$aBIB 001444635 980__ $$aEBOOK 001444635 982__ $$aEbook 001444635 983__ $$aOnline 001444635 994__ $$a92$$bISE