TY - GEN N2 - Precision medicine holds great promise for the treatment of cancer and represents a unique opportunity for accelerated development and application of novel and repurposed therapeutic approaches. Current studies and clinical trials demonstrate the benefits of genomic profiling for patients whose cancer is driven by specific, targetable alterations. However, precision oncologists continue to be challenged by the widespread heterogeneity of cancer genomes and drug responses in designing personalized treatments. Chapters provide a comprehensive overview of the computational approaches, methods, and tools that enable precision oncology, as well as related biological concepts. Covered topics include genome sequencing, the architecture of a precision oncology workflow, and introduces cutting-edge research topics in the field of precision oncology. This book is intended for computational biologists, bioinformaticians, biostatisticians and computational pathologists working in precision oncology and related fields, including cancer genomics, systems biology, and immuno-oncology. DO - 10.1007/978-3-030-91836-1 DO - doi AB - Precision medicine holds great promise for the treatment of cancer and represents a unique opportunity for accelerated development and application of novel and repurposed therapeutic approaches. Current studies and clinical trials demonstrate the benefits of genomic profiling for patients whose cancer is driven by specific, targetable alterations. However, precision oncologists continue to be challenged by the widespread heterogeneity of cancer genomes and drug responses in designing personalized treatments. Chapters provide a comprehensive overview of the computational approaches, methods, and tools that enable precision oncology, as well as related biological concepts. Covered topics include genome sequencing, the architecture of a precision oncology workflow, and introduces cutting-edge research topics in the field of precision oncology. This book is intended for computational biologists, bioinformaticians, biostatisticians and computational pathologists working in precision oncology and related fields, including cancer genomics, systems biology, and immuno-oncology. T1 - Computational methods for precision oncology / AU - Laganà, Alessandro. VL - volume 1361 CN - RC271.G45 N1 - Includes index. ID - 1444834 KW - Cancer KW - Personalized medicine. KW - Bioinformatics. KW - Cancer KW - Médecine personnalisée. KW - Bio-informatique. SN - 9783030918361 SN - 303091836X TI - Computational methods for precision oncology / LK - https://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-3-030-91836-1 UR - https://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-3-030-91836-1 ER -