001445017 000__ 04198cam\a2200529Ia\4500 001445017 001__ 1445017 001445017 003__ OCoLC 001445017 005__ 20230310003808.0 001445017 006__ m\\\\\o\\d\\\\\\\\ 001445017 007__ cr\un\nnnunnun 001445017 008__ 220309s2022\\\\sz\\\\\\o\\\\\001\0\eng\d 001445017 019__ $$a1302740114$$a1302953956$$a1302985667$$a1303054481$$a1303080219$$a1303084587 001445017 020__ $$a9783030833954$$q(electronic bk.) 001445017 020__ $$a303083395X$$q(electronic bk.) 001445017 020__ $$z3030833941 001445017 020__ $$z9783030833947 001445017 0247_ $$a10.1007/978-3-030-83395-4$$2doi 001445017 035__ $$aSP(OCoLC)1302687451 001445017 040__ $$aYDX$$beng$$cYDX$$dGW5XE$$dEBLCP$$dOCLCO$$dOCLCF$$dOCLCQ 001445017 049__ $$aISEA 001445017 050_4 $$aRS199.5 001445017 08204 $$a615/.6$$223 001445017 24500 $$aPharmacokinetics and pharmacodynamics of nanoparticulate drug delivery /$$cJayvadan K. Patel, Yashwant V. Pathak, editors. 001445017 260__ $$aCham, Switzerland :$$bSpringer,$$c2022. 001445017 300__ $$a1 online resource 001445017 500__ $$aIncludes index. 001445017 5050_ $$aPart 1-Modelling of PK/PD for NPDDS -- Introduction to Nanoparticulate Drug Delivery Systems -- Nanoparticle Properties Affecting Pharmacokinetics of NPDDS -- Models Used for Biopharmaceutical Evaluation of NPDDS -- Models Used in the Pharmacokinetic Evaluation of NPDDS -- Models Used in the Pharmacodynamic Evaluation of NPDDS -- Preclinical Animal Models For Experimental Design of Pharmacokinetic Studies of NPDDS -- Pharmacokinetic Modelling Program (PKMP) -- Part 2-PK/PD for Specific Nanocarriers -- Pharmacokinetic and Pharmacodynamics of Liposomal Nanoparticles -- Pharmacokinetics of Polymer Matrix Drugs (NPDDS) -- Pharmacokinetics of Long-Circulating NPDDS -- Metallic Gold Nanoparticles in vivo Pharmacokinetics and X-ray Contrast imaging Studies -- Muco-adhesive NPDDS In Vitro and Pharmacokinetics Studies -- Pharmacokinetic and Tissue Distribution Study of Solid Lipid Nanoparticles -- Factors Affecting the Clearance and Biodistribution of Polymeric Nanoparticles -- PKPD of PLGA-PEG-PLGA Triblock CoPolymeric Micelles -- Part 3-PKPD in Diseased Conditions for NPDDS -- Bridging Bio-Nanoscience and Cancer Nanomedicine -- Clearance Pathways and Tumor Targeting of Imaging Nanoparticles for Diagnostics -- PLGA Nanoparticles for Oral Delivery-Nephrotoxicity and Pharmacokinetic Studies -- Pharmacokinetics of Nanoparticle Systems for Pulmonary Delivery -- In vivo Biodistribution and Pharmacokinetic Studies of NPDDS for Brain Targeting -- Enhanced Bioavailability and Intestinal Uptake Nanoparticles After Oral Delivery -- Nanoparticle Pharmacokinetic Profiling In Vivo Using Magnetic Resonance Imaging. 001445017 506__ $$aAccess limited to authorized users. 001445017 520__ $$aA reference is needed that addresses the recent progress in aspects of PK/PD methods and developments of nanoparticles for novel drug delivery systems. No other consolidated published reference discusses the PK/PD study of nanoparticle drug delivery systems. This book discusses the advantages of nanoparticle drug delivery systems (NPDDS) in enhancing the pharmacokinetics of many drugs that are not easily metabolized or that obtain the desired therapeutic effect with minimum toxicity. The authors provide an overview of biodistribution with a focus on polymer and lipid nanoparticles. This thorough reference is divided into three parts: Modelling, Specific carries and their potential to treat specific diseases. 001445017 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed March 21, 2022). 001445017 650_0 $$aDrug delivery systems. 001445017 650_0 $$aNanomedicine. 001445017 650_0 $$aPharmacokinetics. 001445017 650_0 $$aDrugs$$xPhysiological effect. 001445017 650_6 $$aSystèmes d'administration de médicaments. 001445017 650_6 $$aPharmacocinétique. 001445017 650_6 $$aMédicaments$$xEffets physiologiques. 001445017 655_0 $$aElectronic books. 001445017 7001_ $$aPatel, Jayvadan K. 001445017 7001_ $$aPathak, Yashwant Vishnupant. 001445017 77608 $$iPrint version: $$z3030833941$$z9783030833947$$w(OCoLC)1259046999 001445017 852__ $$bebk 001445017 85640 $$3Springer Nature$$uhttps://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-3-030-83395-4$$zOnline Access$$91397441.1 001445017 909CO $$ooai:library.usi.edu:1445017$$pGLOBAL_SET 001445017 980__ $$aBIB 001445017 980__ $$aEBOOK 001445017 982__ $$aEbook 001445017 983__ $$aOnline 001445017 994__ $$a92$$bISE