001445615 000__ 03892cam\a2200445Ia\4500
001445615 001__ 1445615
001445615 003__ OCoLC
001445615 005__ 20230310003840.0
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001445615 008__ 220401s2022\\\\si\\\\\\o\\\\\000\0\eng\d
001445615 019__ $$a1308796353$$a1309032917$$a1309041970$$a1310336862
001445615 020__ $$a9789811675898$$q(electronic bk.)
001445615 020__ $$a9811675899$$q(electronic bk.)
001445615 020__ $$z9811675880
001445615 020__ $$z9789811675881
001445615 0247_ $$a10.1007/978-981-16-7589-8$$2doi
001445615 035__ $$aSP(OCoLC)1308395527
001445615 040__ $$aYDX$$beng$$cYDX$$dGW5XE$$dEBLCP$$dOCLCO$$dOCLCF$$dN$T$$dUKAHL$$dOCLCQ
001445615 049__ $$aISEA
001445615 050_4 $$aQH588.S83
001445615 08204 $$a616.02/774$$223
001445615 24500 $$aStem cell production:$$bprocesses, practices and regulations /$$cFirdos Alam Khan, editor.
001445615 260__ $$aSingapore :$$bSpringer,$$c2022.
001445615 300__ $$a1 online resource
001445615 5050_ $$aChapter 1. Stem Cell Therapy: Significance and Applications of Stem Cell Products in the Tissue Engineering and Regenerative Medicine -- Chapter 2. GLP Requirements of Stem Cells -- Chapter 3. Current Good Manufacturing Practice (CGMP) Facility and Production of Stem Cell -- Chapter 4. Global Regulatory Frameworks and Quality Standards for Stem Cells Therapy and Regenerative Medicines -- Chapter 5. Stem Cell Bioreactors: Design, Structure and Operation of Stem Cell Bioreactors -- Chapter 6. Stem Cell Culture and Expansion: Role of culture, Types of Cells, Growth Conditions, Media Nutrients, Growth Factors, Growth Phase Cycle -- Chapter 7. UP Scaling of Clinical Grade Stem Cell Production-Upstream Processing (USP) and Downstream Processing (DSP) Operations of Cell Expansion, Harvesting, Detachment, Separation, Washing and Concentration Steps, and the Regulatory Requirements -- Chapter 8. Characterization of Clinical-Grade Stem Cells: Microscopic, Cellular, Molecular, and Functional Characterization of Stem Cells and their Products According to Regulatory Requirements for FDA Approval -- Chapter 9. Stem Cell Safety and Sterility Testing: A Promising Approach in Regenerative Medicine -- Chapter 10. Stem Cells Storage, Packaging and Transportation -- Chapter 11. Stem Cell Clinical Trials and Stem Cell Market.-.
001445615 506__ $$aAccess limited to authorized users.
001445615 520__ $$aThis book examines the technologies and processes for the development and commercial production of stem cells according to cGMP guidelines. The initial chapter of the book discusses the therapeutic potentials of stem cells for the treatment of various diseases, including degenerative disorders and genetic diseases. The book then reviews the recent developments in the cultivation of stem cells in bioreactors, including critical cultural parameters, possible bioreactor configuration and integrations of novel technologies in bioprocess developmental stages. The book also introduces microscopic, molecular, and cellular techniques for characterization of stem cells for regulatory approvals. Further, it describes optimal cell transporting conditions to maintain cell viability and properties. Further, it summarizes characterization strategies of clinical grade stem cells for stem cell therapy. This book is an invaluable contribution to having an academic and industrial understanding with respect to R&D and manufacturing of clinical grade stem cells.
001445615 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed April 12, 2022).
001445615 650_0 $$aStem cells.
001445615 650_6 $$aCellules souches.
001445615 655_0 $$aElectronic books.
001445615 7001_ $$aKhan, Firdos Alam,$$eeditor.
001445615 77608 $$iPrint version:$$z9811675880$$z9789811675881$$w(OCoLC)1273075851
001445615 852__ $$bebk
001445615 85640 $$3Springer Nature$$uhttps://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-981-16-7589-8$$zOnline Access$$91397441.1
001445615 909CO $$ooai:library.usi.edu:1445615$$pGLOBAL_SET
001445615 980__ $$aBIB
001445615 980__ $$aEBOOK
001445615 982__ $$aEbook
001445615 983__ $$aOnline
001445615 994__ $$a92$$bISE