001445667 000__ 03848cam\a2200529Ii\4500 001445667 001__ 1445667 001445667 003__ OCoLC 001445667 005__ 20230310003843.0 001445667 006__ m\\\\\o\\d\\\\\\\\ 001445667 007__ cr\un\nnnunnun 001445667 008__ 220405s2022\\\\sz\\\\\\o\\\\\001\0\eng\d 001445667 019__ $$a1306525334$$a1308395721$$a1308798748 001445667 020__ $$a9783030964054$$q(electronic bk.) 001445667 020__ $$a3030964051$$q(electronic bk.) 001445667 020__ $$z9783030964047$$q(print) 001445667 020__ $$z3030964043 001445667 0247_ $$a10.1007/978-3-030-96405-4$$2doi 001445667 035__ $$aSP(OCoLC)1308976165 001445667 040__ $$aGW5XE$$beng$$erda$$epn$$cGW5XE$$dEBLCP$$dOCLCO$$dYDX$$dOCLCF$$dN$T$$dUKAHL$$dOCLCQ 001445667 049__ $$aISEA 001445667 050_4 $$aQP551 001445667 08204 $$a572/.6$$223 001445667 24500 $$aProtein reviews.$$nVolume 22 /$$cM. Zouhair Atassi, editor. 001445667 264_1 $$aCham, Switzerland :$$bSpringer,$$c2022. 001445667 300__ $$a1 online resource (vii, 132 pages). 001445667 336__ $$atext$$btxt$$2rdacontent 001445667 337__ $$acomputer$$bc$$2rdamedia 001445667 338__ $$aonline resource$$bcr$$2rdacarrier 001445667 4901_ $$aAdvances in experimental medicine and biology, Protein reviews,$$x2520-1905 ;$$v1371 001445667 500__ $$aIncludes index. 001445667 5050_ $$aIntegrated Structural Studies for Elucidating Carotenoid-Protein Interactions -- The Non-continuum Nature of Eukaryotic Transcriptional Regulation -- Photoreceptor Phosphodiesterase (PDE6): Structure, Regulatory Mechanisms, and Implications for Treatment of Retinal Diseases -- Rhodopsin as a Molecular Target to Mitigate Retinitis Pigmentosa -- Elasticity-Associated Functionality and Inhibition of the HIV Protease -- Single-Run Catalysis and Kinetic Control of Human Telomerase Holoenzyme. 001445667 506__ $$aAccess limited to authorized users. 001445667 520__ $$aThe Protein Reviews series serves as a publication vehicle for reviews that focus on crucial contemporary and vital aspects of protein structure, function, evolution and genetics. Volumes are published online first, prior to publication in a printed book. Chapters are selected according to their importance to the understanding of biological systems, relevance to the unravelling of issues associated with health and disease, or impact on scientific or technological advances and developments. Volume 22 presents six review chapters authored by experts in related fields. The first chapter covers carotenoid-protein interactions. Chapter two addresses the non-continuum of eukaryotic transcriptional regulation. The third chapter reviews the structure of the regulatory and catalytic domains of the photoreceptor phosphodiesterase (PDE6) holoenzyme. Chapter four reviews the current knowledge on small molecule compounds that have been evaluated as rhodopsin modulators to be considered as leads for the development of novel therapies for retinitis pigmentosa. Chapter five deals with Plasticity-associated functionality and inhibition of the HIV protease. Finally, chapter six covers single-run catalysis and kinetic control of human telomerase holoenzyme. This volume is intended for research scientists, clinicians, physicians and graduate students in the fields of biochemistry, cell biology, molecular biology, immunology and genetics. . 001445667 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed April 5, 2022). 001445667 650_0 $$aProteins. 001445667 650_6 $$aProtéines. 001445667 655_0 $$aElectronic books. 001445667 7001_ $$aAtassi, M. Zouhair,$$eeditor. 001445667 77608 $$iPrint version:$$z3030964043$$z9783030964047$$w(OCoLC)1292589584 001445667 830_0 $$aAdvances in experimental medicine and biology ;$$vv. 1371. 001445667 830_0 $$aAdvances in experimental medicine and biology.$$pProtein reviews ;$$vv. 22. 001445667 852__ $$bebk 001445667 85640 $$3Springer Nature$$uhttps://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-3-030-96405-4$$zOnline Access$$91397441.1 001445667 909CO $$ooai:library.usi.edu:1445667$$pGLOBAL_SET 001445667 980__ $$aBIB 001445667 980__ $$aEBOOK 001445667 982__ $$aEbook 001445667 983__ $$aOnline 001445667 994__ $$a92$$bISE