@article{1445741, recid = {1445741}, author = {Commisso, Cosimo,}, title = {Macropinocytosis : functions and mechanisms /}, pages = {1 online resource :}, note = {Includes index.}, abstract = {This book presents the functions and mechanisms of macropinocytosis, an actin-driven endocytic uptake process. Key points, including the evolutionary origins of macropinocytosis and major signaling pathways that regulate this uptake mechanism, are highlighted. A wide-array of functions of macropinocytosis are described, including cellular metabolism, cell death, cell migration and antigen presentation. Macropinocytosis has recently been recognized as a critical pathway in disease pathology and treatment. Therefore, a broad overview of macropinocytosis will benefit clinicians, as well as translational and basic research scientists. Moreover, as one of the main clathrin-independent endocytic routes, compiling all the critical information about macropinocytosis in one collection, this book will also be helpful to educators and their students.}, url = {http://library.usi.edu/record/1445741}, doi = {https://doi.org/10.1007/978-3-030-94004-1}, }