TY - GEN AB - This book presents the functions and mechanisms of macropinocytosis, an actin-driven endocytic uptake process. Key points, including the evolutionary origins of macropinocytosis and major signaling pathways that regulate this uptake mechanism, are highlighted. A wide-array of functions of macropinocytosis are described, including cellular metabolism, cell death, cell migration and antigen presentation. Macropinocytosis has recently been recognized as a critical pathway in disease pathology and treatment. Therefore, a broad overview of macropinocytosis will benefit clinicians, as well as translational and basic research scientists. Moreover, as one of the main clathrin-independent endocytic routes, compiling all the critical information about macropinocytosis in one collection, this book will also be helpful to educators and their students. AU - Commisso, Cosimo, CN - QH634 DO - 10.1007/978-3-030-94004-1 DO - doi ID - 1445741 KW - Endocytosis. KW - Cytology. KW - Endocytose. KW - Cytologie. LK - https://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-3-030-94004-1 N1 - Includes index. N2 - This book presents the functions and mechanisms of macropinocytosis, an actin-driven endocytic uptake process. Key points, including the evolutionary origins of macropinocytosis and major signaling pathways that regulate this uptake mechanism, are highlighted. A wide-array of functions of macropinocytosis are described, including cellular metabolism, cell death, cell migration and antigen presentation. Macropinocytosis has recently been recognized as a critical pathway in disease pathology and treatment. Therefore, a broad overview of macropinocytosis will benefit clinicians, as well as translational and basic research scientists. Moreover, as one of the main clathrin-independent endocytic routes, compiling all the critical information about macropinocytosis in one collection, this book will also be helpful to educators and their students. SN - 9783030940041 SN - 3030940047 T1 - Macropinocytosis :functions and mechanisms / TI - Macropinocytosis :functions and mechanisms / UR - https://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-3-030-94004-1 VL - volume 98 ER -