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001445791 001__ 1445791
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001445791 020__ $$a9783030909246$$q(electronic bk.)
001445791 020__ $$a3030909247$$q(electronic bk.)
001445791 020__ $$z9783030909239
001445791 020__ $$z3030909239
001445791 0247_ $$a10.1007/978-3-030-90924-6$$2doi
001445791 035__ $$aSP(OCoLC)1309956517
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001445791 050_4 $$aRS403$$b.O68 2022
001445791 08204 $$a615.1/9$$223/eng/20220414
001445791 24500 $$aOptimization of pharmaceutical processes /$$cAntonios Fytopoulos, Rohit Ramachandran, Panos M. Pardalos, editors.
001445791 264_1 $$aCham :$$bSpringer,$$c[2022]
001445791 264_4 $$c©2022
001445791 300__ $$a1 online resource :$$billustrations (chiefly color).
001445791 336__ $$atext$$btxt$$2rdacontent
001445791 337__ $$acomputer$$bc$$2rdamedia
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001445791 4901_ $$aSpringer optimization and its applications ;$$vvolume 189
001445791 5050_ $$aProcess control and intensification of solution crystallization (Gong) -- Method of characteristics for the efficient simulation of population balance models (D. Braatz) -- Linearized parameter estimation methods for modeled crystallization phenomena using in-line measurements and its application to optimization of partially seeded crystallization in pharmaceutical processes (Hirasawa) -- Mathematical modeling of different breakage PBE kernels using Monte Carlo simulation results (Kumar) -- Optimization of tablet coating Mayur M Patel Continuous twin screw granulation processing (Douroumis) -- Continuous powder feeding: Equipment design and material considerations (Crean) -- Ultrasound for improved encapsulation and crystallization with focus on pharmaceutical applications (Gogate) -- Nonsmooth modeling for simulation and optimization of continuous pharmaceutical manufacturing processes (Patrascu) -- Integrated synthesis, crystallization, filtration and drying of active pharmaceutical ingredients: a model-based digital design framework for process optimization and control (K. Nagy) -- Fast model predictive control of modular systems for continuous manufacturing of pharmaceuticals (D. Braatz). -- Dynamic modeling and control of a continuous biopharmaceutical manufacturing plant (Mansouri) -- Overview of scheduling methods for pharmaceutical production (T. Maravelias) -- Model-based risk assessment of mAb developability (Glassey) -- Design framework and tools for solid drug product manufacturing processes (Sugiyama) -- Challenges and solutions in drug product process development from a material science perspective (Stauffer).
001445791 506__ $$aAccess limited to authorized users.
001445791 520__ $$aOptimization of Pharmaceutical Processes presents contributions from leading authorities in the fields of optimization and pharmaceutical manufacturing. Formulated within structured frameworks, practical examples and applications are given as guidance to apply optimization techniques to most aspects of pharmaceutical processes from design, to lab and pilot scale, and finally to manufacturing. The increasing demand for better quality, higher yield, more efficient-optimized and green pharmaceutical processes, indicates that optimal conditions for production must be applied to achieve simplicity, lower costs and superior yield. The application of such methods in the pharmaceutical industry is not trivial. Quality of the final product is of major importance to human health and the need for deep knowledge of the process parameters and the optimization of the processes are imperative. The volume, which includes new methods as well as review contributions will benefit a wide readership including engineers in pharmaceuticals, chemical, biological, to name just a few.
001445791 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed April 14, 2022).
001445791 650_0 $$aPharmaceutical chemistry.
001445791 650_0 $$aPharmaceutical industry.
001445791 650_0 $$aMathematical optimization.
001445791 650_6 $$aChimie pharmaceutique.
001445791 650_6 $$aIndustrie pharmaceutique.
001445791 650_6 $$aOptimisation mathématique.
001445791 655_7 $$aLlibres electrònics.$$2thub
001445791 655_0 $$aElectronic books.
001445791 7001_ $$aFytopoulos, Antonios,$$eeditor.
001445791 7001_ $$aRamachandran, Rohit,$$eeditor.
001445791 7001_ $$aPardalos, P. M.$$q(Panos M.),$$d1954-$$eeditor.
001445791 77608 $$iPrint version: $$z3030909239$$z9783030909239$$w(OCoLC)1274201862
001445791 830_0 $$aSpringer optimization and its applications ;$$vv. 189.
001445791 852__ $$bebk
001445791 85640 $$3Springer Nature$$uhttps://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-3-030-90924-6$$zOnline Access$$91397441.1
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