Proteins associated with neurodevelopmental disorders / M. Walid Qoronfleh, Musthafa Mohamed Essa, Chidambaram Saravana Babu, editors.
Qoronfleh, M. Walid, editor.; Essa, Musthafa Mohamed, editor.; Babu, Chidambaram Saravana, editor.
2022
QP363.5 .P76 2022
Available Online

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Title Proteins associated with neurodevelopmental disorders / M. Walid Qoronfleh, Musthafa Mohamed Essa, Chidambaram Saravana Babu, editors.
ISBN 9789811597817 (electronic bk.)
9811597812 (electronic bk.)
9789811597800
9811597804
DOI https://doi.org/10.1007/978-981-15-9781-7
Published Singapore : Springer, [2022]
Copyright ©2022
Language English
Description 1 online resource.
Other Standard Identifiers 10.1007/978-981-15-9781-7 doi
Call Number QP363.5 .P76 2022
Dewey Decimal Classification 612.8
Summary This book comprehensively reviews the proteins associated with neurodevelopmental disorders, including autism spectrum disorder (ASD) and attention deficit hyperactivity disorder (ADHD). It also discusses the interactions of the associated-proteins, like bromodomain-containing proteins (BCPs), kinases, synaptic proteins, scaffolding proteins, transcriptional factors, and DNA-binding proteins at the subcellular and molecular levels. The book also explores the potential of these proteins as a druggable target and a biomarker in the neurodevelopmental disorders. The book further explores the recent advancements in understanding the important role of epigenetic factors in predisposition to these diseases. Lastly, it presents genetic factors that lead to variation in gene expression in these diseases, disorders management via diet intervention and the future potential of stem cell therapy.
Access Note Access limited to authorized users.
Source of Description Online resource; title from PDF title page (SpringerLink, viewed April 13, 2022).
Added Author Qoronfleh, M. Walid, editor.
Essa, Musthafa Mohamed, editor.
Babu, Chidambaram Saravana, editor.
Series Nutritional neurosciences.
Available in Other Form Print version: 9789811597800
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Chapter 1. Proteins Commonly Linked to Autism Spectrum Disorder
Chapter 2. Protein Aggregation and Recycling
Chapter 3. Neuron Membrane and Trafficking Protein Kinases (PKA&B) involved in ASD
Chapter 4. Proteomic profiling in children with ASD
Chapter 5. Molecular Protein biomarkers for developing diagnostics and therapeutic interventions.Gene Regulation in Autism. OR Neurodevelopmental Epigenomics
Chapter 6. Chromatin and Epigenetic Regulation in ASD
Chapter 7. Autism and the Scaffolding Protein Neurobeachin
Chapter 8. Genomic Profiling in ADHD subjects
Chapter 9. ADHD and Epigenetics Regulation
Chapter 10. Proteomic Approach in ADHD
Chapter 11. DHD and the Dopamine Transporter (DAT)
Chapter 12. Protein Kinases involved in ADHD
Chapter 13. ADHD and Cell Adhesion Molecule 1 CAM 1 (CADM1 gene)
Chapter 14. ASD and Cell Adhesion Molecule Astrotactin
Chapter 15. Possible therapeutic interventions through proteins in ADHD.

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