TY - GEN N2 - This book offers a comprehensive and state of the art overview of hemophilia management by reviewing all most recent advances and cutting edge information in this fast evolving field. As hemophilia patients are often affected by joint problems it also provides clear guidance on the surgical treatment of musculo-skeletal manifestations. The first part is devoted to the diseases pathophysiology (differentiating hemophilia A and B), genetics, pharmacotherapy including replacement and non-replacement therapy and gene therapy, as well as quality of life issues also related to hemophilia carriers. The second part is then focused on joint problems, ranging from joint health assessment and pain control to surgical treatment of acute hemarthrosis and hemophilic arthropathy, i.e. radiosynovectomy, total joint arthroplasty and arthroscopic joint debridement. Written by experts drawn from leading institutions involved in treatment of hemophilia and related joint problems, this book offers a valuable resource to hematologists, orthopedic surgeons, rehabilitation physicians, radiologists, and pharmacy researchers. DO - 10.1007/978-3-030-93990-8 DO - doi AB - This book offers a comprehensive and state of the art overview of hemophilia management by reviewing all most recent advances and cutting edge information in this fast evolving field. As hemophilia patients are often affected by joint problems it also provides clear guidance on the surgical treatment of musculo-skeletal manifestations. The first part is devoted to the diseases pathophysiology (differentiating hemophilia A and B), genetics, pharmacotherapy including replacement and non-replacement therapy and gene therapy, as well as quality of life issues also related to hemophilia carriers. The second part is then focused on joint problems, ranging from joint health assessment and pain control to surgical treatment of acute hemarthrosis and hemophilic arthropathy, i.e. radiosynovectomy, total joint arthroplasty and arthroscopic joint debridement. Written by experts drawn from leading institutions involved in treatment of hemophilia and related joint problems, this book offers a valuable resource to hematologists, orthopedic surgeons, rehabilitation physicians, radiologists, and pharmacy researchers. T1 - Advances in hemophilia treatment:from genetics to joint health / DA - 2022. CY - Cham, Switzerland : AU - Rodriguez-Merchan, E. C., CN - RC642 PB - Springer, PP - Cham, Switzerland : PY - 2022. ID - 1446112 KW - Hemophilia KW - Hemophilia KW - Joints KW - Hémophilie KW - Hémophilie KW - Articulations SN - 9783030939908 SN - 3030939901 TI - Advances in hemophilia treatment:from genetics to joint health / LK - https://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-3-030-93990-8 UR - https://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-3-030-93990-8 ER -