001446112 000__ 03766cam\a2200493Ia\4500 001446112 001__ 1446112 001446112 003__ OCoLC 001446112 005__ 20230310003939.0 001446112 006__ m\\\\\o\\d\\\\\\\\ 001446112 007__ cr\un\nnnunnun 001446112 008__ 220424s2022\\\\sz\\\\\\o\\\\\000\0\eng\d 001446112 019__ $$a1312266262$$a1312594496$$a1312714401 001446112 020__ $$a9783030939908$$q(electronic bk.) 001446112 020__ $$a3030939901$$q(electronic bk.) 001446112 020__ $$z3030939898 001446112 020__ $$z9783030939892 001446112 0247_ $$a10.1007/978-3-030-93990-8$$2doi 001446112 035__ $$aSP(OCoLC)1312243255 001446112 040__ $$aYDX$$beng$$cYDX$$dGW5XE$$dEBLCP$$dOCLCO$$dOCLCF$$dUKAHL$$dOCLCQ$$dN$T$$dOCLCQ 001446112 049__ $$aISEA 001446112 050_4 $$aRC642 001446112 08204 $$a616.1/57206$$223/eng/20220503 001446112 24500 $$aAdvances in hemophilia treatment:$$bfrom genetics to joint health /$$cE. Carlos Rodríguez-Merchán, editor. 001446112 260__ $$aCham, Switzerland :$$bSpringer,$$c2022. 001446112 300__ $$a1 online resource 001446112 5050_ $$a1. Pathophysiology of hemophilia -- 2. Genetics of Hemophilia A and B -- 3. Inhibitors in Hemophilia A -- 4. Immune Tolerance In Patients with Hemophilia A -- 5. Hemophilia A: New drugs -- 6. Inhibitors in Hemophilia B -- 7. Immune Tolerance Induction in Hemophilia B -- 8. Hemophilia B: New Drugs -- 9. Management of Hemophilia Carriers -- 10. Pharmacoeconomic Aspects in Hemophilia -- 11. Assessment of Joint Health and Outcome Measures in Hemophilia -- 12. Musculoskeletal Medicine in Hemophilia -- 13. Management of Acute Hemarthrosis in Hemophilia (Including Joint Aspiration) -- 14. Hemophilic Arthropathy: Radiosynovectomy -- 15. Hemophilic Arthropathy: Arthroscopic Joint Debridement -- 16. Hemophilic Arthropathy: Total Joint Arthroplasty -- 17. Hemophilic Arthropathy: Other Orthopedic Procedures -- 18. Gene Therapy in Hemophilia: Latest Advances -- 19.A Summary of the Recent Recommendations of the WFH. 001446112 506__ $$aAccess limited to authorized users. 001446112 520__ $$aThis book offers a comprehensive and state of the art overview of hemophilia management by reviewing all most recent advances and cutting edge information in this fast evolving field. As hemophilia patients are often affected by joint problems it also provides clear guidance on the surgical treatment of musculo-skeletal manifestations. The first part is devoted to the diseases pathophysiology (differentiating hemophilia A and B), genetics, pharmacotherapy including replacement and non-replacement therapy and gene therapy, as well as quality of life issues also related to hemophilia carriers. The second part is then focused on joint problems, ranging from joint health assessment and pain control to surgical treatment of acute hemarthrosis and hemophilic arthropathy, i.e. radiosynovectomy, total joint arthroplasty and arthroscopic joint debridement. Written by experts drawn from leading institutions involved in treatment of hemophilia and related joint problems, this book offers a valuable resource to hematologists, orthopedic surgeons, rehabilitation physicians, radiologists, and pharmacy researchers. 001446112 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed May 3, 2022). 001446112 650_0 $$aHemophilia$$xTreatment. 001446112 650_0 $$aHemophilia$$xGenetic aspects. 001446112 650_0 $$aJoints$$xDiseases. 001446112 650_6 $$aHémophilie$$xTraitement. 001446112 650_6 $$aHémophilie$$xAspect génétique. 001446112 650_6 $$aArticulations$$xMaladies. 001446112 655_0 $$aElectronic books. 001446112 7001_ $$aRodriguez-Merchan, E. C.,$$eeditor. 001446112 77608 $$iPrint version:$$z3030939898$$z9783030939892$$w(OCoLC)1287199374 001446112 852__ $$bebk 001446112 85640 $$3Springer Nature$$uhttps://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-3-030-93990-8$$zOnline Access$$91397441.1 001446112 909CO $$ooai:library.usi.edu:1446112$$pGLOBAL_SET 001446112 980__ $$aBIB 001446112 980__ $$aEBOOK 001446112 982__ $$aEbook 001446112 983__ $$aOnline 001446112 994__ $$a92$$bISE