001446134 000__ 06898cam\a2200529Ii\4500 001446134 001__ 1446134 001446134 003__ OCoLC 001446134 005__ 20230310003940.0 001446134 006__ m\\\\\o\\d\\\\\\\\ 001446134 007__ cr\cn\nnnunnun 001446134 008__ 220425s2022\\\\sz\a\\\\o\\\\\001\0\eng\d 001446134 019__ $$a1311155541$$a1311240715$$a1311266428$$a1311312144$$a1311359082$$a1311464493$$a1312159748 001446134 020__ $$a9783030925895$$q(electronic bk.) 001446134 020__ $$a3030925897$$q(electronic bk.) 001446134 020__ $$z9783030925888 001446134 020__ $$z3030925889 001446134 0247_ $$a10.1007/978-3-030-92589-5$$2doi 001446134 035__ $$aSP(OCoLC)1312273242 001446134 040__ $$aGW5XE$$beng$$erda$$epn$$cGW5XE$$dYDX$$dEBLCP$$dOCLCO$$dOCLCQ 001446134 049__ $$aISEA 001446134 050_4 $$aRG480.S7 001446134 08204 $$a618.1/1$$223/eng/20220425 001446134 24500 $$aPolycystic ovary syndrome :$$bcurrent and emerging concepts /$$cLubna Pal, David B. Seifer, editors. 001446134 250__ $$aSecond edition. 001446134 264_1 $$aCham, Switzerland :$$bSpringer,$$c2022. 001446134 300__ $$a1 online resource (1 volume) :$$billustrations (black and white, and color). 001446134 336__ $$atext$$btxt$$2rdacontent 001446134 337__ $$acomputer$$bc$$2rdamedia 001446134 338__ $$aonline resource$$bcr$$2rdacarrier 001446134 500__ $$aPrevious edition: 2014. 001446134 500__ $$aIncludes index. 001446134 5050_ $$aPart I. Epidemiology of Polycystic Ovary Syndrome -- 1. Diagnostic Criteria and Epidemiology of PCOS -- 2. Prevalence, Presentation, and Diagnosis of PCOS in Adolescents -- 3. Polycystic Ovarian Syndrome: A Diagnosis of Exclusion -- Part II. Pathophysiology, Endocrine and Metabolic Milieus of Polycystic Ovary Syndrome -- 4. Recent Advances in the Genetics of Polycystic Ovary Syndrome -- 5. The Hypothalamo-Pituitary Axis in PCOS -- 6. Ovarian Dysfunction in Polycystic Ovary Syndrome (PCOS) -- 7. The Role of the Adrenal Glands in the Hyperandrogenism associated with the Polycystic Ovarian Syndrome -- 8. Insulin Resistance and Lipotoxicity in PCOS: Causes and Consequences -- 9. Obesity, Dysmetabolic and Proinflammatory Milieu of Polycystic Ovary Syndrome -- Part III. Management of Polycystic Ovary Syndrome -- 10. Managing PCOS in the Adolescent -- 11. Managing the PCOS-Related Symptoms of Hirsutism, Acne, and Female Pattern Hair Loss -- 12. Role of Insulin-Sensitizing Drugs in PCOS Management -- 13. Role of Statins & Resveratrol in PCOS Management -- 14. Role of Lifestyle, Diet and Exercise in the Management of Polycystic Ovarian Syndrome -- Part IV. Management of Polycytic Ovary Syndrome Related Infertility -- 15. Managing PCOS-Related Infertility: Ovulation Induction, In Vitro Fertilization, and In Vitro Maturation -- 16. Considerations and Challenges for Pregnancy in Polycystic Ovary Syndrome -- Part V. The Role of Surgery in the Management of Polycystic Ovary Syndrome -- 17. Rationale and considerations for Bariatric Surgery -- 18. Surgical Management of Polycystic Ovary Syndrome: A Contemporary Viewpoint on Place of Ovarian Surgery in PCOS Management -- Part VI. Health Risks and Burden of Polycystic Ovary Syndrome -- 19. PCOS and its Association with Mental Health -- 20. Obstructive Sleep Apnea in Polycystic Ovary Syndrome -- 21. Endometrial cancer and pre-cancer in polycystic ovary syndrome -- 22. Economic Burden of Polycystic Ovary Syndrome -- Part VII. Emerging Concepts in Polycystic Ovary Syndrome -- 23. The Role of Angiogenic Factor Dysregulation in the Pathogenesis of Polycystic Ovarian Syndrome -- 24. Emerging Concepts: Role of Vitamin D Deficiency in the Pathogenesis of PCOS -- 25. Anti-Mullerian Hormone Signaling relevance for pathophysiology of PCOS & implications for novel therapeutic approaches to managing ovulatory dysfunction of PCOS -- 26. Newer Glucose Lowering Medications and Potential Role in Metabolic Management of PCOS -- 27. Intergenerational Implications of PCOS. 001446134 506__ $$aAccess limited to authorized users. 001446134 520__ $$aNow in a completely newly revised and expanded second edition, this comprehensive text presents the current state of the art in our understanding and management of polycystic ovary syndrome (PCOS), the most common hormonal disorder of reproductive aged women. The numerous bothersome symptoms of PCOS include menstrual irregularities, hirsutism, acne, scalp hair thinning, weigh excess and infertility; additionally, as they age, women with PCOS are at a higher risk for metabolic abnormalities such as diabetes and dyslipidemias, as well as for cardiovascular disease and even certain cancers. Despite improvements in our understanding of this condition, the exact cause/s of PCOS remain elusive; genetic, hormonal, metabolic and environmental underpinnings are all suggested as relevant. All chapters have been updated, with eight new chapters added across seven thematic sections. Part one discusses the epidemiology of PCOS in both adults and adolescents. Part two covers the pathophysiology of PCOS, including genetics, the hypothalamo-pituitary-ovarian and the hypothalamo-pituitary-adrenal axes, insulin resistance, inflammation, and obesity. The next three sections present the various management strategies, medical and surgical, for harnessing the symptomatology, including PCOS-related infertility; these chapters include added case material to provide real-world examples of the treatments in action and their efficacy. Part six covers the comorbidities that women with PCOS commonly encounter, such as issues of mental health, sleep disturbances, endometrial hyperplasia, and cancer, as well as examines the economic burden of PCOS. The final section discusses emerging concepts surrounding possible mechanisms and potential therapeutic approaches to PCOS, including angiogenic dysfunction, the role of vitamin D, future potential therapies to targeted AMH signaling. The closing chapter, by familiarizing the readers with the intergenerational implications of PCOS and by raising awareness of potential "ripple effects", aims at alerting the community on a need for vigilance as regards the health of PCOS progeny. With contributions from leaders in the field, Polycystic Ovary Syndrome, Second Edition remains the gold-standard text on this common medical condition and a valuable resource for the wide range of healthcare professionals engaged in caring for the women with PCOS. 001446134 588__ $$aDescription based on print version record. 001446134 650_0 $$aPolycystic ovary syndrome. 001446134 650_6 $$aSyndrome de Stein-Leventhal. 001446134 655_0 $$aElectronic books. 001446134 7001_ $$aPal, Lubna,$$eeditor. 001446134 7001_ $$aSeifer, David B.,$$d1955-$$eeditor.$$1https://isni.org/isni/0000000082051805 001446134 77608 $$iPrint version:$$tPolycystic ovary syndrome.$$bSecond edition.$$dCham : Springer, 2022$$z9783030925888$$w(OCoLC)1295200937 001446134 852__ $$bebk 001446134 85640 $$3Springer Nature$$uhttps://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-3-030-92589-5$$zOnline Access$$91397441.1 001446134 909CO $$ooai:library.usi.edu:1446134$$pGLOBAL_SET 001446134 980__ $$aBIB 001446134 980__ $$aEBOOK 001446134 982__ $$aEbook 001446134 983__ $$aOnline 001446134 994__ $$a92$$bISE