Beta-lactam resistance in gram-negative bacteria : threats and challenges / Mohammad Shahid, Anuradha Singh, Hiba Sami, editors.
Shahid, M. (Mohammad), editor.; Singh, Anuradha (Professor of chemistry), editor.; Sami, Hiba, editor.
2022
QR177
Available Online

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Title Beta-lactam resistance in gram-negative bacteria : threats and challenges / Mohammad Shahid, Anuradha Singh, Hiba Sami, editors.
ISBN 9789811690976 (electronic bk.)
9811690979 (electronic bk.)
9789811690969
9811690960
DOI https://doi.org/10.1007/978-981-16-9097-6
Published Singapore : Springer, 2022.
Language English
Description 1 online resource : illustrations (black and white, and color).
Other Standard Identifiers 10.1007/978-981-16-9097-6 doi
Call Number QR177
Dewey Decimal Classification 616.9/041
Summary This timely book discusses antimicrobial drug resistance, specifically, the resistance against the beta-lactam class of antibiotics by Gram-Negative bacteria. The book is broadly divided into five sections. The first section describes the underlying mechanisms of antimicrobial resistance in Gram-negative bacteria. It gives an insight into the beta-lactamases, their types, classification, inhibitors, etc. The second section delves deep into the genetic basis of resistance. It talks about transposons, integrons, insertion sequences associated with antibiotic-resistant genes. The next section describes phenotypic and molecular methods to detect beta-lactam resistance. The fourth section talks about the epidemiology and prevalence of beta-lactamases in the environment. The last section of the book describes the various therapeutic options to combat this growing public threat of antimicrobial resistance. It talks about the current reserve drugs, as well as the newer antibiotic agents that are in the pipeline. This book is essential for clinical practitioners, students, and researchers in basic and medical microbiology.
Access Note Access limited to authorized users.
Source of Description Description based on print version record.
Added Author Shahid, M. (Mohammad), editor.
Singh, Anuradha (Professor of chemistry), editor.
Sami, Hiba, editor.
Available in Other Form Beta-lactam resistance in gram-negative bacteria.
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Chapter 1. An overview on antibiotic resistance in Gram-negative bacteria
Chapter 2. Trends in B-lactamases classification
Chapter 3. Beta-lactamases and their classification: An Overview
Chapter 4. Class A type beta-lactamases
Chapter 5. Class B type beta-lactamases: treatment strategies
Chapter 6. Class C type beta-lactamases (AmpC - lactamases)
Chapter 7. Class D type - lactamases
Chapter 8. Mobile genetic elements
Chapter 9. Plasmids associated with B- lactamases in bacteria
Chapter 10. Transposons associated with antibiotic resistance genes in Gram-negative bacteria
Chapter 11. Integrons and Insertion sequences associated with beta-lactamases
Chapter 12. Phenotypic methods of detection of B- lactamases- Chapter 13. Molecular methods for detection of- lactamases
Chapter 14. Epidemiology and Prevalence of beta-lactamases and recent resistance pattern in Gram-negative bacteria from environmental reservoirs
Chapter 15. Environmental biofilms as a reservoir of antibiotic resistance and hotspot for genetic exchange in bacteria
Chapter 16. Beta-Lactamase Inhibitor Combinations Targeting Antibiotic Resistance in Gram-negative Bacteria
Chapter 17. Current Reserve drugs
Chapter 18. Newer Antibiotic agents in pipeline
Chapter 19. Adjuvant molecules/compounds in combating bacterial resistance.

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