Gadd45 stress sensor genes / M. Raza Zaidi, Dan A. Liebermann, editors.
Zaidi, M. Raza.; Liebermann, Dan A., 1949-
2022
QH431
Available Online

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Title Gadd45 stress sensor genes / M. Raza Zaidi, Dan A. Liebermann, editors.
Edition Second edition.
ISBN 9783030948047 (electronic bk.)
3030948048 (electronic bk.)
303094803X
9783030948030
DOI https://doi.org/10.1007/978-3-030-94804-7
Publication Details Cham : Springer, 2022.
Language English
Description 1 online resource (159 pages)
Item Number 10.1007/978-3-030-94804-7 doi
Call Number QH431
Dewey Decimal Classification 611/.01816
Summary This second edition is fully updated throughout and covers the emerging evidence that indicates that the Gadd45 family of proteins plays a unique and critical role as sensors of stress, including genotoxic, physiological, and oncogenic stress. It sheds light on the complex cellular stress response, encompassing myriad molecular pathways with a plethora of regulators and effectors. The GADD45 stress response genes encode small (18 kd) nuclear/cytoplasmic proteins. These genes are rapidly induced by a wide variety of endogenous and exogenous stress stimuli. Despite marked similarities, Gadd45 genes are regulated differentially and exhibit functional diversity. Gadd45 proteins respond to physiological and oncogenic stress, and are implicated in cell cycle arrest, DNA demethylation and repair, apoptosis, cell survival, genomic stability, and inflammation. The purpose of this book is to provide a comprehensive overview of the unique global role that Gadd45 proteins play as stress sensors and the molecular pathways involved.
Access Note Access limited to authorized users.
Added Author Zaidi, M. Raza.
Liebermann, Dan A., 1949-
Series Advances in experimental medicine and biology ; v. 1360.
Available in Other Form Gadd45 Stress Sensor Genes.
Linked Resources Online Access
Record Appears in Online Resources > Ebooks
All Resources
GADD45 in Stress Signaling, Cell Cycle Control, and Apoptosis
GADD45 in Development and Cancer
GADD45 in Normal Hematopoiesis and Leukemia
GADD45 in DNA Methylation and DNA Repair
GADD45 Proteins in Immunity
GADD45 in Liver Function and Cancer
GADD45 in Pre-Eclampsia
GADD45 in Senescence
GADD45 in Neuronal Development, Function, and Injury
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