Cancer immunotherapies : solid tumors and hematologic malignancies / Priya Hays, editors.
Hays, Priya, 1968- editor.
2022
RC271.I45
Available Online

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Title Cancer immunotherapies : solid tumors and hematologic malignancies / Priya Hays, editors.
ISBN 9783030963767 (electronic bk.)
3030963764 (electronic bk.)
9783030963750 (print)
3030963756
DOI https://doi.org/10.1007/978-3-030-96376-7
Published Cham, Switzerland : Springer, 2022.
Language English
Description 1 online resource (xvi, 315 pages) : illustrations (some color).
Item Number 10.1007/978-3-030-96376-7 doi
Call Number RC271.I45
Dewey Decimal Classification 616.99/406
Summary This book presents the clinical scope of cancer immunotherapeutic agents for solid tumors and Hematologic malignancies, elaborates on the scientific details of their modes of action, and presents the impact of these agents on oncology, patients and the broader healthcare system. At present, cancer immunotherapies fall broadly into three categories: immune checkpoint inhibitors (ICIs), adoptive T cell therapies, and cancer vaccines which have distinct mechanisms of action. Immune checkpoint inhibitors rely upon disrupting tumor antigen recognition as self by the immune system through inhibition of checkpoint molecules. Adoptive T cell therapies involve the engineering of T cells ex vivo to target and destroy tumor cells. The first part of this book will provide an overview of the discovery and mechanistic details of the technology. The second part will be devoted to elaborating on the clinical outcomes, successes and limitations for specific tumor subtypes, which includes both solid tumors and hematologic malignances for both pediatric and adult populations. As such, the book offers a valuable resource for oncologists, hematologists, and all those seeking an up-to-date overview of cancer immunotherapies.
Access Note Access limited to authorized users.
Source of Description Online resource; title from PDF title page (SpringerLink, viewed May 19, 2022).
Added Author Hays, Priya, 1968- editor.
Series Cancer treatment and research ; v. 183. 2509-8497
Available in Other Form Print version: 9783030963750
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