001446819 000__ 03487cam\a2200541Ii\4500
001446819 001__ 1446819
001446819 003__ OCoLC
001446819 005__ 20230310004019.0
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001446819 019__ $$a1319198199$$a1319213833$$a1321804457
001446819 020__ $$a9783030958954$$q(electronic bk.)
001446819 020__ $$a3030958957$$q(electronic bk.)
001446819 020__ $$z9783030958947
001446819 020__ $$z3030958949
001446819 0247_ $$a10.1007/978-3-030-95895-4$$2doi
001446819 035__ $$aSP(OCoLC)1319076190
001446819 040__ $$aYDX$$beng$$erda$$epn$$cYDX$$dGW5XE$$dEBLCP$$dN$T$$dUKAHL$$dOCLCQ
001446819 049__ $$aISEA
001446819 050_4 $$aRM301.25
001446819 08204 $$a615.1/90113$$223/eng/20220531
001446819 24500 $$aDrug target selection and validation /$$cMarcus T. Scotti, Carolina L. Bellera, editors.
001446819 264_1 $$aCham :$$bSpringer,$$c[2022]
001446819 264_4 $$c©2022
001446819 300__ $$a1 online resource :$$billustrations (chiefly color).
001446819 336__ $$atext$$btxt$$2rdacontent
001446819 337__ $$acomputer$$bc$$2rdamedia
001446819 338__ $$aonline resource$$bcr$$2rdacarrier
001446819 4901_ $$aComputer-aided drug discovery and design
001446819 500__ $$aIncludes index.
001446819 5050_ $$aDrug discovery paradigms: target-based drug discovery -- Drug discovery paradigms: phenotypic-based drug discovery -- Target Identification Approaches in Drug Discovery -- Introduction to target validation -- Structure-based binding pocket detection and druggability assessment -- Network-Based Target Identification -- The Current State of Precision Medicine and Targeted-Cancer Therapies Where are We? -- Metabolic Control Analysis for drug target selection against human diseases -- Progress on open chemoinformatic tools for drug discovery.
001446819 506__ $$aAccess limited to authorized users.
001446819 520__ $$aThe first book in the newly created book series, Computer-Aided Drug Discovery and Design, focuses on the computational aspects of early drug discovery, drug target identification, and validation. It revises current classical paradigms in target and phenotypic-based drug design with still ingrained approximations and concepts and discusses the research in the new network approach concept that include kinetic selectivity and metabolic analysis. Many often-overlooked approximations and concepts in drug discovery are fully covered. Drug Target Selection and Validation includes both introductory sections and research-based sections to be of use to both students and research scientists in drug discovery, design, kinetics and metabolic analysis. Pharmaceutical scientists, pharmaceutics, drug developers, pharmacologists, biomedical researchers in computer science, medicinal chemists, and precision medicine developers benefit from the information provided. The book concludes with a chapter on chemical and structural databases.
001446819 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed May 31, 2022).
001446819 650_0 $$aDrug development$$xComputer simulation.
001446819 650_0 $$aDrugs$$xComputer-aided design.
001446819 655_0 $$aElectronic books.
001446819 7001_ $$aScotti, Marcus T.,$$eeditor.
001446819 7001_ $$aBellera, Carolina L.,$$eeditor.
001446819 77608 $$iPrint version:$$z3030958949$$z9783030958947$$w(OCoLC)1291171598
001446819 830_0 $$aComputer-aided drug discovery and design.
001446819 852__ $$bebk
001446819 85640 $$3Springer Nature$$uhttps://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-3-030-95895-4$$zOnline Access$$91397441.1
001446819 909CO $$ooai:library.usi.edu:1446819$$pGLOBAL_SET
001446819 980__ $$aBIB
001446819 980__ $$aEBOOK
001446819 982__ $$aEbook
001446819 983__ $$aOnline
001446819 994__ $$a92$$bISE