Inorganic polyphosphates : from basic research to medical application / Werner E. G. Müller, Heinz C. Schröder, Patrick Suess, Xiaohong Wang, editors.
Müller, Werner E. G.; Schröder, Heinz C. (Heinz-Christoph); Suess, Patrick.; Wang, Xiaohong, Professor Dr.
2022
QP535.P1
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Title Inorganic polyphosphates : from basic research to medical application / Werner E. G. Müller, Heinz C. Schröder, Patrick Suess, Xiaohong Wang, editors.
ISBN 9783031012372 (electronic bk.)
3031012372 (electronic bk.)
3031012364
9783031012365
DOI https://doi.org/10.1007/978-3-031-01237-2
Publication Details Cham, Switzerland : Springer, 2022.
Language English
Description 1 online resource
Item Number 10.1007/978-3-031-01237-2 doi
Call Number QP535.P1
Dewey Decimal Classification 572
Summary This volume focuses on the biomedical aspects of inorganic polyphosphates, a family of unique bio-inorganic polymers. In recent years, great advances have been made in understanding the development, metabolism, and physiological role of inorganic polyphosphates. These energy-rich polymers, which consist of long chains of phosphate units, are evolutionary old molecules. The acidocalcisomes, conserved organelles from bacteria to humans, as well as the mitochondria play a central role in polyphosphate production and storage. Polyphosphates have been assigned multiple functions, some of which are closely related to medically important processes, such as blood coagulation and fibrinolysis, energy metabolism, cell cycle regulation, apoptosis, chaperon function, microvascularization, stress response, neurodegeneration and aging. The development of bioinspired polyphosphate particles, in combination with suitable hydrogel-forming polymers enabled the development of new strategies in regenerative medicine, in particular for hard and soft tissue repair, but also in drug delivery and antimicrobial defense. This book not only highlights the basic research in this area, but also discusses possible applications. Therefore, it appeals to scientists working in cell biology, biochemistry, and biomedicine and practicioners alike.
Access Note Access limited to authorized users.
Source of Description Online resource; title from PDF title page (SpringerLink, viewed June 27, 2022).
Added Author Müller, Werner E. G.
Schröder, Heinz C. (Heinz-Christoph)
Suess, Patrick.
Wang, Xiaohong, Professor Dr.
Series Progress in molecular and subcellular biology ; 61.
Available in Other Form Print version: 9783031012365
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Chapter 1. Inorganic Polyphosphate and F0F1-ATP Synthase of Mammalian Mitochondria
Chapter 2. Inorganic Polyphosphate in Mitochondrial Energy Metabolism and Pathology
Chapter 3. Inorganic Polyphosphate, Mitochondria, and Neurodegeneration
Chapter 4. Polyphosphate in Chronic Wound Healing: Restoration of Impaired Metabolic Energy State
Chapter 5. Biomimetic Polyphosphate Materials: Towards Application in Regenerative Medicine
Chapter 6. Effects of Polyphosphate on Leukocyte Function
Chapter 7. Polyphosphate in Antiviral Protection: A Polyanionic Inorganic Polymer in the Fight Against Coronavirus SARS-CoV-2 Infection.

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