@article{1448109,
      recid = {1448109},
      author = {Dederer, Hans-Georg, and Hamburger, David},
      title = {Brain organoids in research and therapy : fundamental  ethical and legal aspects /},
      pages = {1 online resource :},
      abstract = {This volume elucidates the pivotal ethical and legal  issues arising from the use of brain organoids for  research, therapeutic and enhancement purposes. The  function of the human brain is still a mystery. Until  recently, only post-mortem tissue was available for a  structural examination of the brain. Consequently, the  examination results could only reflect the state at the end  of life. However, in order to better understand the  development and function of the human brain, dynamic and  functional investigations of different human brain cells  are necessary. This is where brain organoids, artificially  grown in vitro miniature brains, provide the opportunity  for more flexible research scenarios. At the same time,  however, the use of brain organoids in research and therapy  raises the question of how these new entities are to be  treated from an ethical and legal point of view. Against  this background, this volume aims at clarifying the  normative implications of the use of brain organoids in  research and therapy. The ethical reflections on the status  of brain organoids, informed consent, human-to-animal  chimeras and neuro-enhancement are mirrored by  corresponding legal analyses. The ethical and legal  assessments are preceded by an introduction to the  scientific and medical background of the brain organoid  technology. A final chapter will be devoted to the issue of  whether international harmonization of normative standards  for brain organoid research and therapy is feasible and  advisable.},
      url = {http://library.usi.edu/record/1448109},
      doi = {https://doi.org/10.1007/978-3-030-97641-5},
}