001448109 000__ 04801cam\a2200553Ii\4500
001448109 001__ 1448109
001448109 003__ OCoLC
001448109 005__ 20230310004222.0
001448109 006__ m\\\\\o\\d\\\\\\\\
001448109 007__ cr\cn\nnnunnun
001448109 008__ 220712s2022\\\\sz\a\\\\o\\\\\000\0\eng\d
001448109 019__ $$a1335112487
001448109 020__ $$a9783030976415$$q(electronic bk.)
001448109 020__ $$a3030976416$$q(electronic bk.)
001448109 020__ $$z9783030976408
001448109 020__ $$z3030976408
001448109 0247_ $$a10.1007/978-3-030-97641-5$$2doi
001448109 035__ $$aSP(OCoLC)1335119234
001448109 040__ $$aGW5XE$$beng$$erda$$epn$$cGW5XE$$dYDX$$dEBLCP$$dOCLCF$$dOCLCQ
001448109 049__ $$aISEA
001448109 050_4 $$aQP376
001448109 08204 $$a616.02/774$$223/eng/20220712
001448109 24500 $$aBrain organoids in research and therapy :$$bfundamental ethical and legal aspects /$$cHans-Georg Dederer, David Hamburger, editors.
001448109 264_1 $$aCham :$$bSpringer,$$c[2022]
001448109 264_4 $$c©2022
001448109 300__ $$a1 online resource :$$billustrations (chiefly color).
001448109 336__ $$atext$$btxt$$2rdacontent
001448109 337__ $$acomputer$$bc$$2rdamedia
001448109 338__ $$aonline resource$$bcr$$2rdacarrier
001448109 4901_ $$aAdvances in neuroethics
001448109 5050_ $$aChapter 1) Introductory Remarks -- Part I) Scientific Background -- Chapter 2) Development of Brain Organoids on the Basis of Genome-Edited iPSC-Derived Brain Cells -- Chapter 3) Cell-Based Therapy and Genome Editing in Parkinson's Disease: Quo Vadis -- Part II) The Status Debate -- Chapter 4) Human Cerebral Organoids: Evolving Entities and Their Moral Status -- Chapter 5). Legal perspective: What is, or Should Be, the Legal Status of Brain Organoids? -- Part III) The Informed Consent Challenge -- Chapter 6) Ethical Perspective: Ethics Considerations Regarding Donors and Patients Consent -- Chapter 7) The Legal Perspective: The Legal Requirements forand Limits tothe Donors and the Patients Consent -- Part IV) The Chimera Issue -- Chapter 8) Moral Permissibility of Transplantation of Human Brain Organoids into Animals -- Chapter 9) Transplantation of Human Brain Organoids into Animals - The Legal Issues -- Part V) The Enhancement Conundrum -- Chapter 10) Building a Better Beast: Enhancing the Minds of Animals -- Chapter 11) Legal Arguments in Favour of and Against Neuroenhancement by Means of Brain Organoids -- Part VI) The Harmonization Problem -- Chapter 12) Legal Perspective: A Global Harmonisation of Legal Standards for Brain Organoid Research and Therapy?. .
001448109 506__ $$aAccess limited to authorized users.
001448109 520__ $$aThis volume elucidates the pivotal ethical and legal issues arising from the use of brain organoids for research, therapeutic and enhancement purposes. The function of the human brain is still a mystery. Until recently, only post-mortem tissue was available for a structural examination of the brain. Consequently, the examination results could only reflect the state at the end of life. However, in order to better understand the development and function of the human brain, dynamic and functional investigations of different human brain cells are necessary. This is where brain organoids, artificially grown in vitro miniature brains, provide the opportunity for more flexible research scenarios. At the same time, however, the use of brain organoids in research and therapy raises the question of how these new entities are to be treated from an ethical and legal point of view. Against this background, this volume aims at clarifying the normative implications of the use of brain organoids in research and therapy. The ethical reflections on the status of brain organoids, informed consent, human-to-animal chimeras and neuro-enhancement are mirrored by corresponding legal analyses. The ethical and legal assessments are preceded by an introduction to the scientific and medical background of the brain organoid technology. A final chapter will be devoted to the issue of whether international harmonization of normative standards for brain organoid research and therapy is feasible and advisable.
001448109 588__ $$aDescription based on print version record.
001448109 650_0 $$aStem cells.
001448109 650_0 $$aBrain$$xResearch$$xMoral and ethical aspects.
001448109 650_0 $$aBrain$$xDiseases$$xTreatment.
001448109 650_0 $$aMedicine$$xResearch$$xLaw and legislation.
001448109 655_0 $$aElectronic books.
001448109 7001_ $$aDederer, Hans-Georg,$$eeditor.$$1https://isni.org/isni/0000000399607496
001448109 7001_ $$aHamburger, David$$c(Legal researcher),$$eeditor.
001448109 77608 $$iPrint version:$$tBrain organoids in research and therapy.$$dCham : Springer, 2022$$z9783030976408$$w(OCoLC)1328010341
001448109 830_0 $$aAdvances in neuroethics.
001448109 852__ $$bebk
001448109 85640 $$3Springer Nature$$uhttps://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-3-030-97641-5$$zOnline Access$$91397441.1
001448109 909CO $$ooai:library.usi.edu:1448109$$pGLOBAL_SET
001448109 980__ $$aBIB
001448109 980__ $$aEBOOK
001448109 982__ $$aEbook
001448109 983__ $$aOnline
001448109 994__ $$a92$$bISE