001448171 000__ 04788cam\a2200529\a\4500
001448171 001__ 1448171
001448171 003__ OCoLC
001448171 005__ 20230310004225.0
001448171 006__ m\\\\\o\\d\\\\\\\\
001448171 007__ cr\un\nnnunnun
001448171 008__ 220723s2022\\\\sz\\\\\\o\\\\\001\0\eng\d
001448171 019__ $$a1336004388
001448171 020__ $$a9783030989507$$q(electronic bk.)
001448171 020__ $$a303098950X$$q(electronic bk.)
001448171 020__ $$z9783030989491
001448171 020__ $$z3030989496
001448171 0247_ $$a10.1007/978-3-030-98950-7$$2doi
001448171 035__ $$aSP(OCoLC)1336402712
001448171 040__ $$aEBLCP$$beng$$epn$$cEBLCP$$dGW5XE$$dYDX$$dEBLCP$$dOCLCQ$$dOCLCF$$dOCLCQ
001448171 049__ $$aISEA
001448171 050_4 $$aRC270.3.T84
001448171 08204 $$a616.99/407$$223/eng/20220725
001448171 24500 $$aBiomarkers of the tumor microenvironment /$$cLars A. Akslen, Randolph S. Watnick, editors.
001448171 250__ $$a2nd ed.
001448171 260__ $$aCham :$$bSpringer,$$c2022.
001448171 300__ $$a1 online resource (596 pages)
001448171 336__ $$atext$$btxt$$2rdacontent
001448171 337__ $$acomputer$$bc$$2rdamedia
001448171 338__ $$aonline resource$$bcr$$2rdacarrier
001448171 500__ $$aIncludes index.
001448171 5050_ $$aForeword -- Preface -- Prologue -- Basic Studies: Tumor Mechanisms and Tissue Biomarkers -- The Role of the Tumor Microenvironment in Regulating Angiogenesis -- Vessel co-option in melanoma -- Tissue Based Biomarkers of Tumor-Vascular Interactions -- Molecular phenotypes of endothelial cells in malignant tumors -- Lymphatics in malignant tumors -- Role of the Extracellular Matrix in Tumor Stroma Barrier or Support? -- Importance of tissue architecture in cancer development and progression -- The Tumor Microenvironment as a Target for Therapeutic Modulation and Monitoring -- Tumor-fibroblast interactions -- Stromal PDGF Receptors as Prognostic and Predictive Biomarkers -- Inflammation and Cancer, the Role of Lipid Signalling in the Continuum Between Two Ends of the Tumor Spectrum -- Cancer Immunity and Immune Evasion Mechanisms -- Drivers of EMT and Immune Evasion -- Inflammatory Biomarkers for Cancer -- Tumor Infiltrating Lymphocytes: Methods and Guidelines -- The Role of Platelets in the Tumor Microenvironment -- Regulation of Tumor Progression and Metastasis by Bone Marrow-Derived Microenvironments -- Neuropilin 1 and Neuropilin 2: Cancer Progression and Biomarker Analysis -- The Role of Axl Receptor Tyrosine Kinase in Tumor Cell Plasticity and Therapy Resistance -- Imaging mass cytometry in studies of the tumor microenvironment -- Artificial intelligence in studies of malignant tumors -- Clinical Applications: Organ Related Biomarker Studies -- Gene Expression Signatures of the Tumor Microenvironment: Relation to Tumor Progress in Breast Cancer -- MR-Derived Biomarkers for Cancer Characterization -- PDX-models and small animal imaging in studies of gynecologic cancers -- The Influence of Tissue Architecture on Drug Response: Anti-Cancer Drug Development in High-Dimensional Combinatorial Microenvironment Platforms -- Models of Tumor Progression in Prostate Cancer -- Prostate biomarkers -- Immune responses in lung cancer -- Tumor-vascular interactions in non-small cell lung cancer -- Tumor-Host Interactions in Malignant Glioma -- The Tumor Microenvironment in Cutaneous Melanoma Friend or Foe? -- Biomarker Panels and Contemporary Practice in Clinical Trials of Targeted Therapy.
001448171 506__ $$aAccess limited to authorized users.
001448171 520__ $$aThis book reviews different aspects of the cancer microenvironment, and its regulation and importance for tumor progression. Methodological advancements and practical applications, in terms of how biomarkers are studied and increasingly included in clinical trials and therapy protocols, are described and discussed. Biomarkers of the Tumor Microenvironment is an educational resource for students and members of the cancer research community as a whole, especially for those using morphology analysis techniques and models focusing on the cross-talk between different cell types in tumors. The textbook provides a comprehensive overview of the microenvironment in various contexts from the perspectives of experienced and accomplished cancer researchers and clinicians.
001448171 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed July 25, 2022).
001448171 650_0 $$aTumor markers.
001448171 650_0 $$aPathology.
001448171 650_0 $$aOncology.
001448171 655_0 $$aElectronic books.
001448171 7001_ $$aAkslen, Lars A.
001448171 7001_ $$aWatnick, Randolph S.
001448171 77608 $$iPrint version:$$aAkslen, Lars A.$$tBiomarkers of the Tumor Microenvironment.$$dCham : Springer International Publishing AG, ©2022$$z9783030989491
001448171 852__ $$bebk
001448171 85640 $$3Springer Nature$$uhttps://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-3-030-98950-7$$zOnline Access$$91397441.1
001448171 909CO $$ooai:library.usi.edu:1448171$$pGLOBAL_SET
001448171 980__ $$aBIB
001448171 980__ $$aEBOOK
001448171 982__ $$aEbook
001448171 983__ $$aOnline
001448171 994__ $$a92$$bISE