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001448179 001__ 1448179
001448179 003__ OCoLC
001448179 005__ 20230310004225.0
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001448179 008__ 220723s2022\\\\si\\\\\\o\\\\\000\0\eng\d
001448179 019__ $$a1335755555
001448179 020__ $$a9789811913792$$q(electronic bk.)
001448179 020__ $$a981191379X$$q(electronic bk.)
001448179 020__ $$z9789811913785
001448179 020__ $$z9811913781
001448179 0247_ $$a10.1007/978-981-19-1379-2$$2doi
001448179 035__ $$aSP(OCoLC)1336404753
001448179 040__ $$aEBLCP$$beng$$epn$$cEBLCP$$dGW5XE$$dYDX$$dEBLCP$$dOCLCQ$$dOCLCF$$dOCLCQ$$dWAU
001448179 049__ $$aISEA
001448179 050_4 $$aR856
001448179 08204 $$a610.28$$223/eng/20220725
001448179 24500 $$aMicrofluidics and multi organs on chip /$$cP.V. Mohanan, editor.
001448179 260__ $$aSingapore :$$bSpringer,$$c2022.
001448179 300__ $$a1 online resource (ix, 717 pages) :$$billustrations.
001448179 336__ $$atext$$btxt$$2rdacontent
001448179 337__ $$acomputer$$bc$$2rdamedia
001448179 338__ $$aonline resource$$bcr$$2rdacarrier
001448179 5050_ $$aHistorical and technological background to 'organ on a chip' -- Applications of microfluidics -- Microfluidics-based organ-on-a-chip for cell biology studies -- Microfluidics in chemical biology -- Role of microfluidics in drug delivery -- Microfluidics in drug delivery -- Microfludic-based sensors -- Background and organ on a chip -- Culture and co-culture of cells for multi-organ on a chip -- Cells and organs on a chip in biomedical sciences -- Futuristic aspects of human organ on a chip -- Development of Human-on-a-chip -- Multiorgans-on-a-chip for personalized medicine -- Development and application of microfluidicss in organoid formation -- Liver-on-a-chip -- Placenta on chip : a modern approach to probe feto-maternal interface -- Microfluidic retina-on-chip -- Heart-on-a-chip -- Kidney-on-a-chip -- Lung-on-a-chip -- Brain-on-a-chip -- Skin-on-chip -- Organs-on-a-chip in preclinical studies -- Application of organ-on-chip in blood brain barrier model -- Multi-organs-on-a-chip in disease modelling -- Prospects of medical-device-on-a-chip -- Lab-on-a-chip for functional testing for precision medicine -- Tumour-on-a-chip : perfusion systems to model the extracellular breast tumour microenvironment - from tumour progression to metastasis formation -- Building human in vitro 3D models to replace animal studies : during drug discovery research : scientific, ethical and regulatory considerations.
001448179 506__ $$aAccess limited to authorized users.
001448179 520__ $$aThis book highlights the application of microfluidics in cell biology research, chemical biology, and drug discovery. It covers the recent breakthroughs and prospects of organ-on-a-chip, human-on-a-chip, multi-organ-on-a-chip for personalized medicine. The book presents the preclinical studies of organs-on-a-chip, concepts of multiple vascularized organ-on-chips, application of organ-on-a-chip in blood-brain barrier model, culture and co-culture of cells on multi-organ-on-chip and parameter measurements in microfluidic devices. It underscores the advantage of microfluidic devices for developing efficient drug carrier particles, cell-free protein synthesis systems, and rapid techniques for direct drug screening. Further, it entails human-on-a-chip for measuring the systemic response as well as immediate effects of an organ reaction on other organs. In summary, this book reviews the development of a microfluidic-based organ-on-a-chip device for the preclinical evaluation, ADME studies of drugs, chemicals, and medical devices. This book is a valuable source for pharma companies, product developers, students, researchers, academicians, and practitioners.
001448179 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed July 25, 2022).
001448179 650_0 $$aBiomedical engineering.
001448179 650_0 $$aMicrofluidics.
001448179 650_0 $$aArtificial organs.
001448179 655_0 $$aElectronic books.
001448179 7001_ $$aMohanan, P. V.,$$eeditor.
001448179 77608 $$iPrint version:$$aMohanan, P.V.$$tMicrofluidics and Multi Organs on Chip.$$dSingapore : Springer, ©2022$$z9789811913785
001448179 852__ $$bebk
001448179 85640 $$3Springer Nature$$uhttps://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-981-19-1379-2$$zOnline Access$$91397441.1
001448179 909CO $$ooai:library.usi.edu:1448179$$pGLOBAL_SET
001448179 980__ $$aBIB
001448179 980__ $$aEBOOK
001448179 982__ $$aEbook
001448179 983__ $$aOnline
001448179 994__ $$a92$$bISE