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001448403 001__ 1448403
001448403 003__ OCoLC
001448403 005__ 20230310004237.0
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001448403 008__ 220726s2022\\\\sz\\\\\\o\\\\\000\0\eng\d
001448403 019__ $$a1337145203
001448403 020__ $$a9783030999957$$q(electronic bk.)
001448403 020__ $$a3030999955$$q(electronic bk.)
001448403 020__ $$z9783030999940
001448403 020__ $$z3030999947
001448403 0247_ $$a10.1007/978-3-030-99995-7$$2doi
001448403 035__ $$aSP(OCoLC)1337199954
001448403 040__ $$aGW5XE$$beng$$erda$$epn$$cGW5XE$$dYDX$$dEBLCP$$dOCLCF$$dN$T$$dOCLCQ
001448403 049__ $$aISEA
001448403 050_4 $$aRC628
001448403 08204 $$a616.3/98$$223/eng/20220726
001448403 24500 $$aFrom obesity to diabetes /$$cJuergen Eckel, Karine Clément, editors.
001448403 264_1 $$aCham :$$bSpringer,$$c[2022]
001448403 264_4 $$c©2022
001448403 300__ $$a1 online resource (viii, 513 pages).
001448403 336__ $$atext$$btxt$$2rdacontent
001448403 337__ $$acomputer$$bc$$2rdamedia
001448403 338__ $$aonline resource$$bcr$$2rdacarrier
001448403 4901_ $$aHandbook of experimental pharmacology,$$x1865-0325 ;$$vvolume 274
001448403 5050_ $$aPart I Obesity. Epidemiology of Obesity -- The Circadian Clock and Obesity -- Nutrition and Microbiome -- From Obesity to Diabetes: The Role of the Adipose Organ -- Targeting Epicardial Fat in Obesity and Diabetes Pharmacotherapy -- The Enteroendocrine System in Obesity -- Insights from Studies of White Adipose Tissue Using Single-Cell Approaches -- Obesity-Related Insulin Resistance: The Central Role of Adipose Tissue Dysfunction -- Obesity, Senescence, and Senolytics -- Obesity and Obstructive Sleep Apnea -- Part II Diabetes and Complications. Inter-Organ Crosstalk in the Development of Obesity-Associated Insulin Resistance -- Islet Inflammation and [beta] Cell Dysfunction in Type 2 Diabetes -- NAFLD and NASH: The Metabolically Diseased Liver -- Diabetic Kidney Disease: From Pathogenesis to Novel Treatment Possibilities -- Diabetic Peripheral Neuropathy -- Part III Lifestyle Modifications and Future Treatments. Weight Loss Strategies -- Physical Activity, Obesity and Weight Loss Maintenance -- Bariatric/Metabolic Surgery -- Drugs for Treating Obesity -- Novel Drugs for Diabetes Therapy -- Novel Approaches to Restore Pancreatic Beta-Cell Mass and Function -- Precision Medicine and Obesity -- Targeting the Enteroendocrine System for Treatment of Obesity.
001448403 506__ $$aAccess limited to authorized users.
001448403 520__ $$aObesity is a major risk factor for the development of type 2 diabetes and its associated complications, a major socio-economic burden for health care systems. The worldwide prevalence of obesity doubled since 1980 and as a consequence the number of patients with diabetes has been continuously rising with more than 450 Mio. people suffering from this disease at the present time. Substantial progress has been made in understanding the molecular pathways leading from excessive fat accumulation to metabolic perturbation and finally diabetes manifestation. This edition of the "Handbook of Experimental Pharmacology" aims to analyze new insight into the pathophysiology of obesity, to decipher the complex links to diabetes and its complications, and to collect most recent information on new strategies for prevention and treatment of obesity and diabetes.
001448403 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed July 26, 2022).
001448403 650_0 $$aObesity$$xPathophysiology.
001448403 650_0 $$aType 2 diabetes$$xPathophysiology.
001448403 655_0 $$aElectronic books.
001448403 7001_ $$aEckel, Juergen,$$eeditor.
001448403 7001_ $$aClément, Karine,$$d1966-$$eeditor.
001448403 77608 $$iPrint version:$$z3030999947$$z9783030999940$$w(OCoLC)1302739360
001448403 830_0 $$aHandbook of experimental pharmacology ;$$vv. 274.$$x1865-0325
001448403 852__ $$bebk
001448403 85640 $$3Springer Nature$$uhttps://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-3-030-99995-7$$zOnline Access$$91397441.1
001448403 909CO $$ooai:library.usi.edu:1448403$$pGLOBAL_SET
001448403 980__ $$aBIB
001448403 980__ $$aEBOOK
001448403 982__ $$aEbook
001448403 983__ $$aOnline
001448403 994__ $$a92$$bISE