TY - GEN N2 - This book, which is the third volume of Biomedical translational research, focuses on the fundamental role of biomedical research in developing new medicinal products. It emphasizes the importance of understanding biological and pathophysiological mechanisms underlying the disease to discover and develop new biological agents. The book uniquely explores the genomic computational integrative approach for drug repositioning. Further, it discusses the health benefits of nutraceuticals and their application in human diseases. Further, the book comprehensively reviews different computational approaches that employ GWAS data to guide drug repositioning. Finally, it summarizes the major challenges in drug development and the strategies for the rational design of the next generation more effective but less toxic therapeutic agents. DO - 10.1007/978-981-16-9232-1 DO - doi AB - This book, which is the third volume of Biomedical translational research, focuses on the fundamental role of biomedical research in developing new medicinal products. It emphasizes the importance of understanding biological and pathophysiological mechanisms underlying the disease to discover and develop new biological agents. The book uniquely explores the genomic computational integrative approach for drug repositioning. Further, it discusses the health benefits of nutraceuticals and their application in human diseases. Further, the book comprehensively reviews different computational approaches that employ GWAS data to guide drug repositioning. Finally, it summarizes the major challenges in drug development and the strategies for the rational design of the next generation more effective but less toxic therapeutic agents. T1 - Biomedical translational research :drug design and discovery / DA - 2022. CY - Singapore : AU - Sobti, R. C. AU - Dhalla, Naranjan S. CN - RS420 PB - Springer, PP - Singapore : PY - 2022. N1 - 5.3.3.2 Cystic Fibrosis ID - 1448601 KW - Drugs KW - Biomedical engineering SN - 9789811692321 SN - 9811692327 TI - Biomedical translational research :drug design and discovery / LK - https://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-981-16-9232-1 UR - https://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-981-16-9232-1 ER -