001448698 000__ 04071cam\a2200565\i\4500 001448698 001__ 1448698 001448698 003__ OCoLC 001448698 005__ 20230310004252.0 001448698 006__ m\\\\\o\\d\\\\\\\\ 001448698 007__ cr\cn\nnnunnun 001448698 008__ 220814s2022\\\\sz\a\\\\o\\\\\001\0\eng\d 001448698 019__ $$a1340956612 001448698 020__ $$a9783030977443$$q(electronic bk.) 001448698 020__ $$a3030977447$$q(electronic bk.) 001448698 020__ $$z9783030977436 001448698 020__ $$z3030977439 001448698 0247_ $$a10.1007/978-3-030-97744-3$$2doi 001448698 035__ $$aSP(OCoLC)1340946645 001448698 040__ $$aYDX$$beng$$erda$$epn$$cYDX$$dGW5XE$$dEBLCP$$dOCLCF$$dVLB$$dOCLCQ 001448698 049__ $$aISEA 001448698 050_4 $$aRC271.I45$$bC27 2022eb 001448698 08204 $$a616.99/4061$$223/eng/20220819 001448698 24500 $$aCardio-oncology :$$bmanagement of toxicities in the era of immunotherapy /$$cAntonio Russo, Nicola Maurea, Dimitrios Farmakis, Antonio Giordano, editors. 001448698 264_1 $$aCham :$$bHumana Press,$$c[2022] 001448698 264_4 $$c©2022 001448698 300__ $$a1 online resource (xiv, 122 pages : illustrations (some color)). 001448698 336__ $$atext$$btxt$$2rdacontent 001448698 337__ $$acomputer$$bc$$2rdamedia 001448698 338__ $$aonline resource$$bcr$$2rdacarrier 001448698 4901_ $$aCurrent clinical pathology 001448698 500__ $$aIncludes index. 001448698 50500 $$tBackground: Immunology and Cancer --$$tAvailable Immunotherapy Drugs in Oncology --$$tImmunotherapy Adverse Events --$$tPathophysiology of Cardiac Toxicity --$$tDiagnostic Methods of Cardiac Immunotherapy Damaging --$$tBiomarkers of Early Cardiotoxicity --$$tManagement of Patients with Cardiac Toxicity: The Point of View of the Cardiologist --$$tManagement of Patients with Cardiac Toxicity: The Point of View of the Oncologist --$$tFuture perspectives. 001448698 506__ $$aAccess limited to authorized users. 001448698 520__ $$aThe development of immunotherapy in oncology field has revolutionized the prognosis of many types of cancer. The immune checkpoint inhibitors target receptors whose inhibition increases the activity of immune system cells against tumor cells. In recent years, new immunotherapies have been studied and approved in a growing number of tumors including melanoma, non-small cell lung cancer (NSCLC), and renal cell cancer (RCC). This volume provides a complete and updated state-of-art review regarding the management of cardiovascular toxicities from new immunotherapies. The manuscript is divided into different sections starting from the relationship between cancer and immune system to let the reader understand the new molecular concepts under immunotherapy development. Subsequent chapters describe specifically the immunotherapy options in solid tumor treatment and the main features of the immuno-related cardiovascular complications. This volume is written by experts in the oncological and cardiovascular fields and aims to provide to clinicians who approach current cancer patients a useful tool to move through the paths of modern cardio-oncology. An important section would afford the most relevant interventions needed to manage the cardiac events, suggesting how to reduce their impact and effects on oncological outcomes. The text concludes by addressing future perspectives in the cardio-immunology field, discussing many aspects such as the early detection of cardiovascular damage and the potential role of liquid biopsy in new damage-related biomarkers discovery. 001448698 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed August 19, 2022). 001448698 650_0 $$aCancer$$xImmunotherapy$$xComplications. 001448698 650_0 $$aCardiovascular toxicology. 001448698 655_0 $$aElectronic books. 001448698 7001_ $$aRusso, Antonio,$$d1956-$$eeditor. 001448698 7001_ $$aMaurea, Nicola,$$eeditor. 001448698 7001_ $$aFarmakis, Dimitrios,$$eeditor. 001448698 7001_ $$aGiordano, Antonio,$$cMD,$$eeditor. 001448698 77608 $$iPrint version: $$z3030977439$$z9783030977436$$w(OCoLC)1295351569 001448698 830_0 $$aCurrent clinical pathology. 001448698 852__ $$bebk 001448698 85640 $$3Springer Nature$$uhttps://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-3-030-97744-3$$zOnline Access$$91397441.1 001448698 909CO $$ooai:library.usi.edu:1448698$$pGLOBAL_SET 001448698 980__ $$aBIB 001448698 980__ $$aEBOOK 001448698 982__ $$aEbook 001448698 983__ $$aOnline 001448698 994__ $$a92$$bISE