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001449187 001__ 1449187
001449187 003__ OCoLC
001449187 005__ 20230310004347.0
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001449187 008__ 220903s2022\\\\si\a\\\\o\\\\\000\0\eng\d
001449187 019__ $$a1343250044
001449187 020__ $$a9789811929762$$q(electronic bk.)
001449187 020__ $$a9811929769$$q(electronic bk.)
001449187 020__ $$z9789811929755
001449187 020__ $$z9811929750
001449187 0247_ $$a10.1007/978-981-19-2976-2$$2doi
001449187 035__ $$aSP(OCoLC)1343197518
001449187 040__ $$aYDX$$beng$$erda$$epn$$cYDX$$dGW5XE$$dEBLCP$$dOCLCF$$dOCLCQ
001449187 049__ $$aISEA
001449187 050_4 $$aQH324.2
001449187 08204 $$a610.285$$223/eng/20220913
001449187 24500 $$aBlockchain in life sciences /$$cWendy Charles, editor.
001449187 264_1 $$aSingapore :$$bSpringer,$$c[2022]
001449187 264_4 $$c©2022
001449187 300__ $$a1 online resource (xxvii, 336 pages) :$$billustrations (some color).
001449187 336__ $$atext$$btxt$$2rdacontent
001449187 337__ $$acomputer$$bc$$2rdamedia
001449187 338__ $$aonline resource$$bcr$$2rdacarrier
001449187 4901_ $$aBlockchain technologies
001449187 5050_ $$aIntro -- Foreword -- Preface -- Acknowledgments -- Contents -- About the Editor -- Abbreviations -- List of Figures -- List of Tables -- Blockchain Uses and Real World Evidence -- Introduction to Blockchain -- 1 Introduction -- 2 Blockchain Core Characteristics -- 2.1 Ledgers -- 2.2 Cryptography -- 2.3 Immutability (Tamper Evidence and Tamper Resistance) -- 2.4 Distribution -- 3 Blockchain Features -- 3.1 Permissionless Versus Permissioned -- 3.2 Permissionless -- 3.3 Off-Chain Versus On-Chain Storage -- 3.4 Smart Contracts -- 4 Blockchain Benefits for Life Sciences -- 4.1 Trust
001449187 5058_ $$a4.2 Audit Trails-Provenance -- 4.3 Data Transparency Versus Privacy -- 4.4 Security -- 4.5 Performance -- 5 Conclusions -- 6 Key Terminology and Definitions -- References -- Blockchain in Pharmaceutical Research and the Pharmaceutical Value Chain -- 1 Brief Overview of Pharmaceutical Research -- 1.1 Drug Delivery and Discovery -- 1.2 Challenges Associated with Drug Delivery and Discovery -- 1.3 Challenges Associated with Preclinical (i.e., In Vitro, In Vivo) and Phase 0/I-IV Studies -- 2 Introduction of the End-To-End Pharmaceutical Value Chain
001449187 5058_ $$a2.1 Five Main Categories: (1) Research and Discovery, (2) Clinical Development, (3) Manufacturing and Supply Chain, (4) Launch and Commercial Considerations, and (5) Monitoring and Health Records -- 2.2 Differentiating Pharmaceutical Value Chain from Pharmaceutical Supply Chain -- 3 Blockchain Efforts Within Pharmaceutical Industry -- 3.1 Pharmaceutical Users Software Exchange (PhUSE) Blockchain Project -- 3.2 Innovative Medicines Initiative (IMI) Blockchain-Enabled Healthcare
001449187 5058_ $$a3.3 The MELLODDY Project and Millions of Molecules Blockchain + Smart Contracts for Human Participant Regulations and Consent Management -- 3.4 Information Exchange and Data Transformation (INFORMED) Initiative -- 3.5 Moneyball Medicine -- 4 Mapping Blockchain Characteristics to Pain Points in the Pharmaceutical Value Chain -- 4.1 Adapted Fit-For-Purpose Framework and Design Elements -- 4.2 Matching Characteristics (e.g., Decentralized, Distributed, Conditionally Immutable, Scalable, Cryptographically Secured) to Identified Pain Points in Each of the 5 Categories
001449187 5058_ $$a5 Blockchain-But Not in a Vacuum -- 5.1 Blockchain-Complementary Established and Emerging (e.g., Machine Learning, Artificial Intelligence) Technologies for the Pharmaceutical Value Chain -- 6 Debunking Myths Around Challenges with Blockchain -- 6.1 The Myth of the Technical Challenge -- 6.2 The Reality of Challenges Tied to Change Management, Resource Allocation, Paradigm Shift, and Reaching Consensus -- 7 Blockchain and The Idea Pipeline -- 7.1 Pharmacogenomics -- 7.2 Collaborative Pharmaceutical Development -- 7.3 Patient Access, Medication Reclamation, and Prescription Waste Reduction
001449187 506__ $$aAccess limited to authorized users.
001449187 520__ $$aThis book highlights the latest advances on the implementation and adaptation of blockchain technologies in real-world scientific, biomedical, and data applications. It presents rapid advancements in life sciences research and development by applying the unique capabilities inherent in distributed ledger technologies. The book unveils the current uses of blockchain in drug discovery, drug and device tracking, real-world data collection, and increased patient engagement used to unlock opportunities to advance life sciences research. This paradigm shift is explored from the perspectives of pharmaceutical professionals, biotechnology start-ups, regulatory agencies, ethical review boards, and blockchain developers. This book enlightens readers about the opportunities to empower and enable data in life sciences.
001449187 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed September 13, 2022).
001449187 650_0 $$aLife sciences$$xData processing.
001449187 650_0 $$aBlockchains (Databases)
001449187 655_0 $$aElectronic books.
001449187 7001_ $$aCharles, Wendy,$$eeditor.
001449187 77608 $$iPrint version: $$z9811929750$$z9789811929755$$w(OCoLC)1310396952
001449187 77608 $$iPrint version:$$tBlockchain in life sciences.$$dSingapore : Springer Nature Singapore, 2022$$z9789811929755$$w(OCoLC)1338678673
001449187 830_0 $$aBlockchain technologies (Series)
001449187 852__ $$bebk
001449187 85640 $$3Springer Nature$$uhttps://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-981-19-2976-2$$zOnline Access$$91397441.1
001449187 909CO $$ooai:library.usi.edu:1449187$$pGLOBAL_SET
001449187 980__ $$aBIB
001449187 980__ $$aEBOOK
001449187 982__ $$aEbook
001449187 983__ $$aOnline
001449187 994__ $$a92$$bISE