001449371 000__ 03972cam\a2200517\i\4500 001449371 001__ 1449371 001449371 003__ OCoLC 001449371 005__ 20230310004357.0 001449371 006__ m\\\\\o\\d\\\\\\\\ 001449371 007__ cr\cn\nnnunnun 001449371 008__ 220909s2022\\\\sz\a\\\\o\\\\\001\0\eng\d 001449371 019__ $$a1342984262$$a1343249688 001449371 020__ $$a9783031054600$$q(electronic bk.) 001449371 020__ $$a3031054601$$q(electronic bk.) 001449371 020__ $$z9783031054594 001449371 020__ $$z3031054598 001449371 0247_ $$a10.1007/978-3-031-05460-0$$2doi 001449371 035__ $$aSP(OCoLC)1344015308 001449371 040__ $$aGW5XE$$beng$$erda$$epn$$cGW5XE$$dEBLCP$$dYDX$$dOCLCF$$dOCLCQ 001449371 049__ $$aISEA 001449371 050_4 $$aRC365 001449371 08204 $$a616.8/0471$$223/eng/20220909 001449371 24500 $$aUnderstanding PTMs in neurodegenerative diseases /$$cVictor Corasolla Carregari, editor. 001449371 264_1 $$aCham :$$bSpringer,$$c2022. 001449371 300__ $$a1 online resource :$$billustrations (black and white). 001449371 336__ $$atext$$btxt$$2rdacontent 001449371 337__ $$acomputer$$bc$$2rdamedia 001449371 338__ $$aonline resource$$bcr$$2rdacarrier 001449371 4901_ $$aAdvances in experimental medicine and biology. Proteomics, metabolomics, interactomics and systems biology ;$$v1382 001449371 5050_ $$aProtein extraction and sample preparation methods for shotgun proteomics with central nervous system cells and brain tissue -- Phosphopeptide enrichment techniques: a pivotal step for phosphoproteomic studies -- Post-Translational Modifications during Brain Development -- Aberrant protein glycosylation in brain cancers, with emphasis on glioblastoma -- Post-Translational Modification in Muscular Dystrophies -- Post-translational Modifications in Parkinsons Disease -- Histone Modifications in Neurological Disorders -- Mitochondrial dysregulation and the influence in neurodegenerative diseases -- PTMs: A missing piece for schizophrenia studies -- Post-Translational Modifications in Brain Diseases: A Future for Biomarkers -- Index. 001449371 506__ $$aAccess limited to authorized users. 001449371 520__ $$aThis new volume, a part of the Proteomics, Metabolomics, Interactomics and Systems Biology series, will explain how proteomic studies of post-translational modifications (PTMs) can be applied to neurodegenerative diseases and relevant studies. The goal of the book is to increase awareness among researchers about how PTMs may be helpful in understanding mechanisms in various neurodegenerative diseases through proteomic studies. This book will serve as a tool for those who want to begin work in the proteomics field and explore how to implement PTMs studies into their work. Chapter authors will describe different PTMs enrichment methods developed by experts in the field so that researchers may learn to apply these methods and techniques to new studies. Divided into three sections, chapters will cover sample preparation, data quality, enrichment techniques, guidelines on how to analyze PTMs, and explain the role of PTMs and different brain diseases. Among those topics includes will be brain cancer, SLA disease, Parkinsons disease, muscular dystrophies, and schizophrenia. This volume will be useful for researchers and students studying brain and neurodegenerative diseases who are interested in delving into work with proteomic studies and PTMs. . 001449371 588__ $$aDescription based on print version record. 001449371 650_0 $$aNervous system$$xDegeneration. 001449371 650_0 $$aProteomics. 001449371 650_0 $$aMetabolism. 001449371 655_0 $$aElectronic books. 001449371 7001_ $$aCarregari, Victor Corasolla,$$eeditor. 001449371 77608 $$iPrint version:$$tUnderstanding PTMs in neurodegenerative diseases.$$dCham : Springer, 2022$$z9783031054594$$w(OCoLC)1328004285 001449371 830_0 $$aAdvances in experimental medicine and biology.$$pProteomics, metabolomics, interactomics and systems biology ;$$v1382. 001449371 852__ $$bebk 001449371 85640 $$3Springer Nature$$uhttps://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-3-031-05460-0$$zOnline Access$$91397441.1 001449371 909CO $$ooai:library.usi.edu:1449371$$pGLOBAL_SET 001449371 980__ $$aBIB 001449371 980__ $$aEBOOK 001449371 982__ $$aEbook 001449371 983__ $$aOnline 001449371 994__ $$a92$$bISE